Abstract
In acute tonsillitis, group A streptococci (GAS) is the etiological agent in 30–50% of cases. The reported frequencies of clinical and bacterial treatment failure following penicillin therapy range from 10 to 25%, increasing if treatment is reduced from 10 to 7 days. The MIC value of GAS for penicillin V (pcV) is 0.004–0.03 mg/l by the plate dilution and 0.008–0.03 by the broth dilution technique (2). Resistant strains have not been isolated in vivo but according to some investigations, penicillin tolerance may be one cause of treatment failure (6).
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© 1997 Springer Science+Business Media New York
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Stjernquist-Desatnik, A., Orrling, A., Schalén, C., Kamme, C. (1997). Lack of Penicillin Tolerance in Group A Streptococci. In: Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H., Sicard, M. (eds) Streptococci and the Host. Advances in Experimental Medicine and Biology, vol 418. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1825-3_104
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