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Focal and Generalized Epileptiform Activity in the Cortex: In Search of Differences in Synaptic Mechanisms, Ionic Movements, and Long-Lasting Changes in Neuronal Excitability

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Generalized Epilepsy

Abstract

The aim of this chapter is to compare the cellular and the ionic mechanisms that characterize the focal and generalized epileptiform discharges recorded in the cortex. In this review of experimental findings obtained in both in vivo and in vitro brain preparations, we have set as our goal understanding the differences that might exist at the cellular level in these epileptic patterns in humans.

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Authors
  1. M. Avoli
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  2. P. Gloor
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  3. G. Kostopoulos
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Editor information

Editors and Affiliations

  1. Montreal Neurological Institute, Department of Neurophysiology, McGill University, H3A 2B4, Montreal, Quebec, Canada

    Massimo Avoli M.D., Ph.D.  & Pierre Gloor Ph.D.  & 

  2. Department of Physiology, University of Patras Medical School, 261 10, Patras, Greece

    George Kostopoulos M.D., Ph.D.

  3. Laboratoire de Physiologie Nerveuse, CNRS, F-91198, Gif-sur-Yvette, France

    Robert Naquet M.D.

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Avoli, M., Gloor, P., Kostopoulos, G. (1990). Focal and Generalized Epileptiform Activity in the Cortex: In Search of Differences in Synaptic Mechanisms, Ionic Movements, and Long-Lasting Changes in Neuronal Excitability. In: Avoli, M., Gloor, P., Kostopoulos, G., Naquet, R. (eds) Generalized Epilepsy. Birkhäuser Boston. https://doi.org/10.1007/978-1-4684-6767-3_15

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  • DOI: https://doi.org/10.1007/978-1-4684-6767-3_15

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4684-6769-7

  • Online ISBN: 978-1-4684-6767-3

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