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Oncogenes and Breast Cancer Progression

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Boundaries between Promotion and Progression during Carcinogenesis

Part of the book series: Basic Life Sciences ((BLSC,volume 57))

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Abstract

The etiology of breast cancer is thought to involve a complex interplay of genetic, hormonal, and dietary factors that are superimposed on the physiological status of the host. Extensive studies have been undertaken to determine the relationship between these factors and tumor development in humans and experimental rodent models. Attempts to develop a cohesive picture of how these factors participate in mammary tumorigenesis have been hampered, in part, by a lack of information on the specific genetic lesions that contribute to the initiation and/or evolution of tumor development.

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Authors and Affiliations

  1. Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

    Robert Callahan (Chief, Oncogenetics Section)

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  1. Robert Callahan
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Editors and Affiliations

  1. Case Western Reserve University, Cleveland, Ohio, USA

    Oscar Sudilovsky

  2. McArdle Laboratory for Cancer Research, Madison, Wisconsin, USA

    Henry C. Pitot

  3. National Institutes of Health, Bethesda, Maryland, USA

    Lance A. Liotta

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© 1991 Plenum Press, New York

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Callahan, R. (1991). Oncogenes and Breast Cancer Progression. In: Sudilovsky, O., Pitot, H.C., Liotta, L.A. (eds) Boundaries between Promotion and Progression during Carcinogenesis. Basic Life Sciences, vol 57. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5994-4_13

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  • DOI: https://doi.org/10.1007/978-1-4684-5994-4_13

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