Skip to main content

Sources and Significance of Variation as Measured in Human Populations

  • Chapter
Phenotypic Variation in Populations

Part of the book series: Basic Life Sciences ((BLSC,volume 43))

Abstract

Our commission is to discuss the nature and meaning of variation and yet to avoid overlap with the comments of our distinguished colleagues. As theorists, we shall take a somewhat abstract approach; and as physicians we shall try to extend it to include the level of human subtlety.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Boiling, D. R., and Murphy, E. A., 1979, Finite sample properties of maximum likelihood estimates of the recombination fraction in double backcross matings in man. Am J Med Genet 3: 81–95.

    Article  Google Scholar 

  • Cannon, W. B., 1932, “The Wisdom of the Body.” Norton, New York.

    Google Scholar 

  • Cantor, C. R., and Schimmel, P. R. Schimmel, 1980, “Biophysical Chemistry.” Freeman, San Francisco.

    Google Scholar 

  • Chung, K. L., 1974, “A Course in Probability Theory.” Academic Press, New York.

    Google Scholar 

  • Crow, J. F., 1958, Some possibilities for measuring selection intensities in man. Hum Biol 30 1.

    PubMed  CAS  Google Scholar 

  • Fisher, R. A., 1936, Has Mendel’s work been rediscovered? Annals Science 1:115.

    Article  Google Scholar 

  • Green, M. C., 1981, “Genetic Variants and Strains of the Laboratory Mouse.” Gustav Fischer Verlag, Stuttgart.

    Google Scholar 

  • Kuhn, T., 1970, “The Structure of Scientific Revolutions”. Second edition. University of Chicago Press, Chicago.

    Google Scholar 

  • Leder, P., 1982, The genetics of antibody diversity. Scientific Amer. 246:102.

    Article  CAS  Google Scholar 

  • Lyon, M. F., 1972, X-chromosome inactivation and developmental patterns in mammals. Biol. Rev. Cambridge Phil. Soc. 47:1.

    Article  CAS  Google Scholar 

  • Mandelbrot, B., 1983, “The Fractal Geometry of Nature.” Freeman, New York.

    Google Scholar 

  • McDougal, W., 1948, “Outline of Psychology.” Methuen London, (1948).

    Google Scholar 

  • Moreno, A., and Murphy, E. A., 1981, Inheritance of Kartegener syndrome. Amer. J. Med. Genet. 9:219.

    Article  Google Scholar 

  • Murphy, E. A., 1981, “Skepsis, Dogma and Belief. Uses and Abuses in Medicine.” Johns Hopkins University Press, Baltimore.

    Google Scholar 

  • Murphy, E. A., 1978, Genetic and evolutionary fitness. Amer. J. Med. Genet. 2:51.

    Article  CAS  Google Scholar 

  • Murphy, E. A., and Trojak, J. E., 1986, The genetics of quantifiable homeostasis: 1. The General Issues. Amer. J. Med. Genet. 24:159.

    Article  CAS  Google Scholar 

  • Murphy, E. A., and Berger, K. R., 1987, The dynamics of angular homeostasis: 1. General principles. Amer. J. Med. Genet. 26:457.

    Article  CAS  Google Scholar 

  • Murphy, E. A., 1970, Incomplete penetrance and the ascertainment of recessive characters in man. 1. Introduction and distribution theory. J. Chron. Pis. 23:9.

    Article  CAS  Google Scholar 

  • Nitecki, Z., 1971, “Differentiable dynamics.” Massachusetts Institute of Technology Press, Cambridge, Mass.

    Google Scholar 

  • Olsen, L. F., and Degn, H., 1985, Chaos in Biological Systems. Quarterly Review Biophysics 18:165.

    Article  CAS  Google Scholar 

  • Ott, J., 1985, “Analysis of Human Genetic Linkage.” Johns Hopkins University Press, Baltimore.

    Google Scholar 

  • Ruelle, D., 1977, Sensitive dependence on initial condition and turbulent behavior of dynamical systems. “Bifurcation Theory and Applications in Scientific Disciplines.” Annals of the New York Academy of Sciences, vol 316. New York Academy of Sciences, New York.

    Google Scholar 

  • von Frisch, K., 1950, “Bees: Their Vision, Chemical Senses, and Language.” Cornell University Press, Ithica.

    Google Scholar 

  • Wiener, N., 1848, “Cybernetics or Control and Communication in the Animal and the Machine.” Wiley, New York.

    Google Scholar 

  • Wolff, C., 1980, “The New Grove Bach Family.” Norton, London.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Plenum Press, New York

About this chapter

Cite this chapter

Murphy, E.A., Berger, K.R. (1988). Sources and Significance of Variation as Measured in Human Populations. In: Woodhead, A.D., Bender, M.A., Leonard, R.C. (eds) Phenotypic Variation in Populations. Basic Life Sciences, vol 43. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5460-4_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-5460-4_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5462-8

  • Online ISBN: 978-1-4684-5460-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics