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GTP Activates Two Enzymes of Pyrimidine Salvage from the Human Intestinal Parasite Giardia Intestinalis

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Purine and Pyrimidine Metabolism in Man VII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 309B))

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Abstract

Giardia intestinalis (also referred to as Giardia lamblia) is an anaerobic flagellated parasitic protozoan which infects the human small intestine, leading to a spectrum of disorders, including severe diarrhoea, abdominal pain, anorexia and stunted growth in children1. Giardiasis is listed by the World Health Organisation as one of the ten leading parasitic diseases of humans. About 200 million people are affected world wide each year in both developed and developing countries. Although rarely life threatening on its own, it represents a major public health problem, particularly in children and contributes significantly to malnutrition.

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© 1991 Plenum Press, New York

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O’Sullivan, W.J., Jiminez, B.M., Dai, Y.P., Lee, C.S. (1991). GTP Activates Two Enzymes of Pyrimidine Salvage from the Human Intestinal Parasite Giardia Intestinalis. In: Harkness, R.A., Elion, G.B., Zöllner, N. (eds) Purine and Pyrimidine Metabolism in Man VII. Advances in Experimental Medicine and Biology, vol 309B. Springer, New York, NY. https://doi.org/10.1007/978-1-4615-7703-4_55

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  • DOI: https://doi.org/10.1007/978-1-4615-7703-4_55

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4615-7705-8

  • Online ISBN: 978-1-4615-7703-4

  • eBook Packages: Springer Book Archive

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