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Non-Cholinergic Therapies of Dementia

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Dementia

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Abstract

Numerous pathological processes can cause cognitive impairment in old people. Common causes include Alzheimer’s disease (about 50%), cerebrovascular disease (about 20%), mixed Alzheimer and cerebrovascular changes (about 20%), drug-abuse (most frequently alcohol, about 3%, but can be confounded by other sedative-hypnotic drugs) and miscellaneous aetiologies that include subcortical dementia, normal pressure hydrocephalus, metabolic/endocrine disease and head trauma. In the substantial majority of instances, cognitive impairment is irreversible. A chronic, progressive disease leads to neuronal loss, severe social incapacity and eventual death. However, amongst the miscellaneous aetiologies listed above, a small number of cognitively impaired old people prove on investigation to have suffered a remediable cause of apparent dementia. Figure 28.1 summarizes these causes and their treatment. The investigation and treatment of cognitive impairment in old people forms part of good medical practice and is an essential component of the effective liaison between specialists in geriatric medicine and the psychiatry of old age.

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Authors
  1. L. Whalley
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  2. S. Bailey
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Editors and Affiliations

  1. University of Manchester, UK

    Alistair Burns (Professor of Old Age Psychiatry) (Professor of Old Age Psychiatry)

  2. Institute of Psychiatry, London, UK

    Raymond Levy (Professor of Old Age Psychiatry) (Professor of Old Age Psychiatry)

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© 1994 Springer Science+Business Media Dordrecht

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Whalley, L., Bailey, S. (1994). Non-Cholinergic Therapies of Dementia. In: Burns, A., Levy, R. (eds) Dementia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6805-6_28

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  • DOI: https://doi.org/10.1007/978-1-4615-6805-6_28

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4615-6807-0

  • Online ISBN: 978-1-4615-6805-6

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