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Comparative Genomics

  • Book
  • © 2000

Overview

Editors:
  1. Melody S. Clark

    1. Fugu Genomics HGMP Resource Centre, Wellcome Genome Campus, Cambridge, UK

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Table of contents (8 chapters)

  1. Front Matter

    Pages i-viii
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  2. Comparative Genomics: An Introduction: Sequencing Projects and Model Organisms

    • Melody S. Clark
    Pages 1-22

  3. Drosophila Melanogaster: A Genetic Tool

    • Ulrich Schäfer, Herbert Jäckle
    Pages 23-41

  4. Tunicates: Models for Chordate Evolution and Development at Low Genomic Complexity

    • William R. Jeffery
    Pages 43-69

  5. Fugu Rubripes: A Fish Model Genome

    • Melody S. Clark, Greg Elgar
    Pages 71-96

  6. The Mouse and the Genomic Era

    • Trevor J. Wilson, Francesca Lazner, Ismail Kola, Paul J. Hertzog
    Pages 97-121

  7. Quantitative Trait Loci in Domestic Animals - Complex Inheritance Patterns

    • Ehud Lipkin, Morris Soller
    Pages 123-151

  8. Comparative Genomics of Vertebrates and the Evolution of Sex Chromosomes

    • Jennifer A. Marshall Graves, Swathi Shetty
    Pages 153-205

  9. Insights into Mammalian Genome Organization and Evolution by Molecular Cytogenetics

    • J. Wienberg, L. Frönicke, R. Stanyon
    Pages 207-244

  10. Back Matter

    Pages 245-246
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Keywords

About this book

Since the advent of the Human Genome Project, an increasing number of disease-causing genes have been discovered and, in some cases, genetic tests developed. However, this is only the first step. The second, much larger phase is the analysis of the total sequence. What does the rest of the DNA do? The answer to this question will be determined by computer prediction, expression profiling, and comparative genome analysis.
Comparative Genomics covers such topics as identifying novel genes, determining gene function, control sequences, and developmental switches. The book aims to demonstrate how different approaches taken with model organisms, such as mutation studies, expression profiling of cDNAs, in situ localization of message and comparative genome analysis (both at the gene and nucleotide level) will aid in our understanding of the results coming out of the Human Genome Project and contribute significantly to our understanding of how genes function.

Editors and Affiliations

  • Fugu Genomics HGMP Resource Centre, Wellcome Genome Campus, Cambridge, UK

    Melody S. Clark

Bibliographic Information

  • Book Title: Comparative Genomics

  • Editors: Melody S. Clark

  • DOI: https://doi.org/10.1007/978-1-4615-4657-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2000

  • Hardcover ISBN: 978-0-412-83080-8Published: 30 November 2000

  • Softcover ISBN: 978-1-4613-7107-6Published: 27 September 2012

  • eBook ISBN: 978-1-4615-4657-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 246

  • Topics: Human Genetics, Biochemistry, general, Zoology, Life Sciences, general

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