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Graves’ Disease pp 9–18Cite as

Epidemiology of Graves’ Disease

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Part of the book series: Endocrine Updates ((ENDO,volume 6))

Abstract

It has been estimated that over 3 million Americans currently have Graves’ disease of whom over 41,000 are children (1). Graves’ disease is associated with considerable morbidity, a decrease in quality of life and sufferers incur considerable health care costs. Yet the disease has been neglected by epidemiologists and as a result relatively little is known about its prevalence in the population and its social or biological antecedents.

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References

  1. Jacobson DL, Gange SJ, Rose NR, Graham NMH. 1997 Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin Immunol Immunopathol. 84:223–243.

    Article  PubMed  CAS  Google Scholar 

  2. Furszyfer J, Kurland LT, McConahey WM, Elveback LR. 1970 Graves’ disease in Olmsted county, Minnesota. 1935 through 1967. Mayo Clin Proc. 45:636–644.

    PubMed  CAS  Google Scholar 

  3. Cox SP, Phillips DIW, Osmond C. 1989 Does infection initiate Graves disease?: a population based 10 year study. Autoimmunity. 4:43–49.

    Article  PubMed  CAS  Google Scholar 

  4. Phillips DIW, Barker DJP, Rees Smith B, Didcote S, Morgan D. 1985 The geographical distribution of thyrotoxicosis in England according to the presence or absence of TSH-receptor antibodies. Clin Endocrinol. 23:283–287.

    Article  CAS  Google Scholar 

  5. Thjodleifsson B. 1975 A study of Graves’ disease in Iceland. Acta Med Scand. 198:309–314.

    Article  PubMed  CAS  Google Scholar 

  6. Berglund J, Christensen SB, Hallengren B. 1990 Total and age-specific incidence of Graves’ thyrotoxicosis, toxic nodular goitre and solitary toxic adenoma in Malmö 1970–74. J Int Med. 227:137–141.

    Article  CAS  Google Scholar 

  7. Laurberg P, Pedersen KM, Vestergaard H, Sigurdsson G. 1991 High incidence of multinodular toxic goitre in the elderly population in a low iodine intake area vs. high incidence of Graves’ disease in the young in a high iodine intake area: comparative surveys of thyrotoxicosis epidemiology in East-Jutland Denmark and Iceland. J Lab Clin Med. 229:415–420.

    CAS  Google Scholar 

  8. Haraldsson A, Gudmundsson ST, Larusson G, Sigurdsson G. 1985 Thyrotoxicosis in Iceland 1980–1982. Acta Med Scand. 217:253–258.

    Article  PubMed  CAS  Google Scholar 

  9. Brownlie BEW, Wells JE. 1990 The epidemiology of thyrotoxicosis in New Zealand: incidence and geographical distribution in North Canterbury. Clin Endocrinol. 33:249–259.

    Article  CAS  Google Scholar 

  10. Westphal SA. 1994 Seasonal variation in the diagnosis of Graves’ disease. Clin Endocrinol. 41:27–30.

    Article  CAS  Google Scholar 

  11. Phillips DIW, Barker DJP, Morris JA. 1985 Seasonality of thyrotoxicosis. J Epidem Commun Health. 39:72–74.

    Article  CAS  Google Scholar 

  12. Phillips DIW. 1997 Iodine, milk and the elimination of endemic goitre:the story of an accidental public health triumph. J Epidem Commun Health. 51:391–393.

    Article  CAS  Google Scholar 

  13. Iversen K. 1948 Temporary rise in the frequency of thyrotoxicosis in Denmark. Copenhagen: Rosenkilde & Bagger.

    Google Scholar 

  14. Trowell HC. Non-infective disease in Africa. 1960 London: Edward Arnold, p286

    Google Scholar 

  15. Kalk WJ. 1981 Thyrotoxicosis in urban black Africans: a rising incidence. S Afr J Med. 52:109–116.

    Google Scholar 

  16. Bartley GB, Fatourechi V, Kadrmas EF, et al. 1995 The incidence of Graves’ ophthalmopathy in Olmsted County, Minnesota. Amer J Ophthal. 120:511–517.

    PubMed  CAS  Google Scholar 

  17. Tellez M, Cooper J, Edmonds C. 1992 Graves’ Ophthalmopathy in relation to cigarette smoking and ethnic origin. Clin Endocrinol. 36:291–294.

    Article  CAS  Google Scholar 

  18. Hagg E, Asplund K. 1987 Is endocrine ophthalmopathy related to smoking? Brit Med J. 295:634–635.

    Article  CAS  Google Scholar 

  19. Bartalena L, Bogazzi F, Tanda ML, Manetti L, Dell’Unto E, Martino E. 1995 Cigarette smoking and the thyroid. Eur J Endocrinol. 133:507–512.

    Article  PubMed  CAS  Google Scholar 

  20. Shine B, Fells P, Edwards OM, Weetman AP. 1990 Association between Graves’ ophthalmopathy and smoking. Lancet. 335:1261–1263.

    Article  PubMed  CAS  Google Scholar 

  21. Winsa B, Mandahl A, Karlsson FA. 1993 Graves’ disease, endocrine ophthalmopathy and smoking. Acta Endocrinol (Copenh). 128:156–160.

    CAS  Google Scholar 

  22. Prummel MF, Wiersinga WM. 1993 Smoking and risk of Graves’ disease. JAMA. 269:479–482.

    Article  PubMed  CAS  Google Scholar 

  23. Yoshiuchi K, Kumano H, Nomura S, et al. 1998 Stressful life events and smoking were associated with Graves’ disease in women, but not in men. Psychosom Med. 60:182–185.

    PubMed  CAS  Google Scholar 

  24. Caleb Hillier Parry. 1932 Hyperthyroidism. In: Major RH, ed. Classic descriptions of disease. Oxford: Blackwell, pp 275–279.

    Google Scholar 

  25. Hobbs JR. 1992 Stress and Graves’ disease. Lancet. 339:427–428.

    Article  PubMed  CAS  Google Scholar 

  26. Gray J, Hoffenberg R. 1985 Thyrotoxicosis and stress. Q J Med. 54:153–160.

    PubMed  CAS  Google Scholar 

  27. Winsa B, Adami HO, Bergstrom R, et al. 1991 Stressful life events and Graves’ disease. Lancet. 338:1475–1479.

    CAS  Google Scholar 

  28. Sonino N, Girelli ME, Boscaro M, Fallo F, Busnardo B, Fava GA. 1993 Life events in the pathogenesis of Graves’ disease. A controlled study. Acta Endocrinol (Copenh). 128:293–296.

    CAS  Google Scholar 

  29. Kung A.W. 1995 Life events, daily stresses and coping in patients with Graves’ disease. Clin Endocrinol. 42:303–308.

    Article  CAS  Google Scholar 

  30. Harris T, Creed F, Brugha TS. 1992 Stressful life events and Graves’ disease. Br J Psychiatry. 161:535–541.

    CAS  Google Scholar 

  31. Gripenberg M, Miettinen A, Kurki P, Linder E. 1978 Indirect immunofluorescence and anti-epithelial antibodies in Yersinial infections. Arthritis Rheum. 21:904–908.

    Article  PubMed  CAS  Google Scholar 

  32. Shenkman L, Bottone EJ. 1976 Antibodies to Yersinia enterocolitica in thyroid disease. Ann Int Med. 85:735–739.

    PubMed  CAS  Google Scholar 

  33. Keddie N, Metcalfe-Gibson C, Tooth JA. 1977 Yersinia and thyroid disease. Lancet. (ii):1368

    Article  Google Scholar 

  34. Weetman AP, McGregor AM. 1994 Autoimmune thyroid disease: further developments in our understanding. Endocr Rev. 15:788–830.

    PubMed  CAS  Google Scholar 

  35. Barker DJP, Phillips DIW. 1984 Current incidence of hyperthyroidism and past prevalence of endemic goitre in 12 British towns. Lancet. (ii):567–570.

    Article  Google Scholar 

  36. Safran M, Paul TL, Roti E, Braverman LE. 1987 Environmental factors affecting autoimmune thyroid disease. Endocrinol Metab Clin N Amer. 16:327–342.

    CAS  Google Scholar 

  37. Mostbeck A, Galvan G, Bauer P, et al. 1998 The incidence of hyperthyroidism in Austria from 1987 to 1995 before and after an increase in salt iodization in 1990. Eur J Nucl Med. 25:367–374.

    Article  PubMed  CAS  Google Scholar 

  38. Hancock SL, Cox RS, McDougall IR. 1991 Thyroid diseases after treatment of Hodgkin’s disease. N Engl J Med. 325:599–605.

    Article  PubMed  CAS  Google Scholar 

  39. Phillips DIW. 1985 The Epidemiology of hyperthyroidism in England and Wales. PhD Thesis, University of Southampton pp 51–52.

    Google Scholar 

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Authors
  1. David Phillips
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Editors and Affiliations

  1. Autoimmune Disease Unit, Cedars-Sinai Research Institute and U.C.L.A. School of Medicine, Los Angeles, California, USA

    Basil Rapoport M.B., Ch.B.  & Sandra M. McLachlan Ph.D  & 

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© 2000 Springer Science+Business Media New York

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Phillips, D. (2000). Epidemiology of Graves’ Disease. In: Rapoport, B., McLachlan, S.M. (eds) Graves’ Disease. Endocrine Updates, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4407-4_2

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  • DOI: https://doi.org/10.1007/978-1-4615-4407-4_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6983-7

  • Online ISBN: 978-1-4615-4407-4

  • eBook Packages: Springer Book Archive

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