Abstract
Germinal centers of stimulated lymphoid follicules comprise different microenvironments where B cells proliferate or differentiate into memory B cells or precursors of Ig-producing cells [1]. Follicular dendritic cells (FDC), unique non lymphoid cells, mainly compose these microenvironments. FDC are closely associated with B cells and can be distinguished from other accessory cells in secondary lymphoid tissues by a number of features, as lack of phagocytic activity and a characteristic set of cell surface markers.
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Bosseloir, A.L., Defrance, T., Bouzahzah, F., Heinen, E., Simar, L.J. (1995). Modulation of B Lymphocyte Proliferation Inside the Germinal Center. In: Banchereau, J., Schmitt, D. (eds) Dendritic Cells in Fundamental and Clinical Immunology. Advances in Experimental Medicine and Biology, vol 378. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1971-3_74
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DOI: https://doi.org/10.1007/978-1-4615-1971-3_74
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