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The Alcohol Dehydrogenase System

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Enzymology and Molecular Biology of Carbonyl Metabolism 5

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 372))

Abstract

Alcohol dehydrogenases of different types are common enzymes in nature. Two of these families, the medium-chain dehydrogenase/reductase family, MDR, and the shortchain dehydrogenase/reductase family, SDR, are well studied and known since long, but have experienced a recent “explosion” of new knowledge, extension and importance. The MDR family includes the classical zinc-containing liver alcohol dehydrogenases encompassing the classes of human liver alcohol dehydrogenase, while the SDR family includes the Drosophila alcohol dehydrogenase, which has shorter subunits, no similar metal requirements, other sub-domain arrangements with different structural relationships, and other subunit interactions.

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Authors and Affiliations

  1. Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77, Stockholm, Sweden

    Hans Jörnvall, Olle Danielsson, Lars Hjelmqvist, Bengt Persson & Jawed Shafqat

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  1. Hans Jörnvall
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  2. Olle Danielsson
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  3. Lars Hjelmqvist
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  4. Bengt Persson
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  5. Jawed Shafqat
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Editors and Affiliations

  1. Purdue University, West Lafayette, Indiana, USA

    Henry Weiner

  2. Griffith University, Brisbane, Queensland, Australia

    Roger S. Holmes

  3. Inselspital, Berne, Switzerland

    Bendicht Wermuth

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Jörnvall, H., Danielsson, O., Hjelmqvist, L., Persson, B., Shafqat, J. (1995). The Alcohol Dehydrogenase System. In: Weiner, H., Holmes, R.S., Wermuth, B. (eds) Enzymology and Molecular Biology of Carbonyl Metabolism 5. Advances in Experimental Medicine and Biology, vol 372. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1965-2_34

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  • DOI: https://doi.org/10.1007/978-1-4615-1965-2_34

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5808-4

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