Abstract
The lung dynamics in ARDS are characterized by alveolar units with different time constants. This is due to the nonhomogenous distribution of the disease in the alveoli, where the changes in compliance and airways resistance cause an unequal distribution of pressure and volume during mechanical ventilation. This nonhomogenous distribution of time constants results in ventilation inhomogeneity. A multi breath indicator gas washout technique has recently been reported to measure this inhomogeneity.1
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Kesecioglu, J., Ince, C., Pompe, J.C., Gütuna, I., Erdmann, W., Bruining, H.A. (1994). Effect of Ketanserine on Oxygenation and Ventilation Inhomogeneity in Pigs with ARDS. In: Hogan, M.C., Mathieu-Costello, O., Poole, D.C., Wagner, P.D. (eds) Oxygen Transport to Tissue XVI. Advances in Experimental Medicine and Biology, vol 361. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-1875-4_78
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DOI: https://doi.org/10.1007/978-1-4615-1875-4_78
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