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Immunologic approaches to the classification of non-Hodgkin’s lymphomas

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Immunologic Approaches to the Classification and Management of Lymphomas and Leukemias

Part of the book series: Cancer Treatment and Research ((CTAR,volume 38))

Abstract

This chapter employs the working formulation (WF) of the non-Hodgkin’s lymphomas as a histologic base, because its ten morphologic categorizations are well defined and of established clinical utility, identifying prognostic gradations relevant to therapy [1]. Using this firm histologic base, the immunologic characteristics within each category are emphasized. As this chapter repeatedly demonstrates, many immunologic subtypes exist within certain WF categories, and these cannot always be predicted by morphologic classification [2]. Figure 1A details the WF categorizations relevant to the previously widely used Rappaport classification [3]. Figure 1B details some closely related entities to be discussed. Some of these represent lymphoma-related diseases, others represent newer categorizations derived from immunologic studies (e.g., peripheral T-cell lymphoma).

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Authors
  1. Thomas M. Grogan
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  2. Catherine M. Spier
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  3. Lynne C. Richter
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  4. Catherine S. Rangel
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Editor information

Editors and Affiliations

  1. University of Rochester Cancer Center, Rochester, New York, 14642, USA

    John M. Bennett

  2. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, 48109, USA

    Kenneth A. Foon

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© 1988 Kluwer Academic Publishers

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Grogan, T.M., Spier, C.M., Richter, L.C., Rangel, C.S. (1988). Immunologic approaches to the classification of non-Hodgkin’s lymphomas. In: Bennett, J.M., Foon, K.A. (eds) Immunologic Approaches to the Classification and Management of Lymphomas and Leukemias. Cancer Treatment and Research, vol 38. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1713-5_2

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  • DOI: https://doi.org/10.1007/978-1-4613-1713-5_2

  • Publisher Name: Springer, Boston, MA

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  • Online ISBN: 978-1-4613-1713-5

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