Abstract
Little is known about the distribution of lead in the human tibia on a microscopic scale. The radial distribution of lead in a 2-mm thick section of the human femur has been measured by Lindh et al. (1978), who observed that the concentration peaked in a region close to the periosteal and endosteal surfaces. The distribution in the interior of the bone was relatively uniform with the exception of a peak located about 1.8 mm from the periphery along a straight radial scan from periosteum to endosteum. Lindh (1980; 1981) also mapped the distribution of lead over a single osteon and showed that the concentration was highest at the edges.
Research supported by NIH Biotechnology Research Resource GRant No. P41RR01838 (GS, KWJ); NIH/SBIR Grant No. 2R44ES03918-02 (DEB,FLM), and NIEHS ST Grant No. 32ES07069 (HH).
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References
Lindh, U., Brune, D., and Nordberg, G., 1978, Microprobe analysis of lead in human femur by proton induced x-ray emission (PIXE), Sci. Tot. Envir., 10:31.
Lindh, U., 1980, A nuclear microprobe investigation of heavy-metal distribution in individual osteons of human femur. Int. J. App Rad. and Isotopes., 31:737.
Lindh, U., 1981, The nuclear microprobe applied to bioenvironmental studies, Nucl. Instrum and Meth., 181:171.
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© 1990 Plenum Press, New York
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Schidlovsky, G., Jones, K.W., Burger, D.E., Milder, F.L., Hu, H. (1990). Distribution of Lead in Human Bone: II. Proton Microprobe Measurements. In: Yasumura, S., Harrison, J.E., McNeill, K.G., Woodhead, A.D., Dilmanian, F.A. (eds) In Vivo Body Composition Studies. Basic Life Sciences, vol 55. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1473-8_37
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DOI: https://doi.org/10.1007/978-1-4613-1473-8_37
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