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Hemodialysis with Cuprophane Membranes Leads to Alteration of Granulocyte Oxidative Metabolism and Leukocyte Sequestion in the Lung

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Proteases II

Abstract

Transient leukopenia1 and change in pulmonary function2 are known to occur regular during the initial phase of hemodialysis (HD) with cuprophane membranes, suggesting that an intrapulmonary sequestration of granulocytes may happen3. Besides this, hypoxemia, complement-activation, increase of granulocyte adherence and enhanced release of granular enzymes have been reported4,5,6. In addition, alteration of granulocyte behavior such as activation of phagocytosis and impaired oxidative metabolism7,8 has been described.

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© 1988 Plenum Press, New York

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Kolb, G. et al. (1988). Hemodialysis with Cuprophane Membranes Leads to Alteration of Granulocyte Oxidative Metabolism and Leukocyte Sequestion in the Lung. In: Hörl, W.H., Heidland, A. (eds) Proteases II. Advances in Experimental Medicine and Biology, vol 240. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1057-0_45

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  • DOI: https://doi.org/10.1007/978-1-4613-1057-0_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8313-3

  • Online ISBN: 978-1-4613-1057-0

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