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Human T-Cell Responses in Leishmania Infections

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Progress in Clinical Parasitology

Abstract

Leishmaniasis is a major public health problem in several areas of the world, occurring in large areas of the Middle East, Africa, and Latin America. The Leishmania complex is a group of closely related parasites that occupy a wide variety of ecologic niches and cause a spectrum of clinical disease. Infection is initiated by the bite of a sandfly, which injects the motile form, called promastigotes. Once inside the mammalian host, Leishmania are obligatory intramacrophage parasites, multiplying in these cells as nonmotile amastigotes. Basic biologic aspects of the parasite are thoroughly reviewed elsewhere (1,2).

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Authors
  1. Donna M. Russo
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  2. Manoel Barral-Netto
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  3. Aldina Barral
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  4. Steven G. Reed
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Editors and Affiliations

  1. Division of Clinical Pathology, North Shore University Hospital, Cornell University Medical College, 300 Community Drive, Manhasset, NY, 11030, USA

    Tsieh Sun M.D. (Professor and Chief) (Professor and Chief)

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Russo, D.M., Barral-Netto, M., Barral, A., Reed, S.G. (1993). Human T-Cell Responses in Leishmania Infections. In: Sun, T. (eds) Progress in Clinical Parasitology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2732-8_5

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