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Allergic Bronchopulmonary Aspergillosis in Patients with Cystic Fibrosis

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Cystic Fibrosis

Part of the book series: Allergy and Immunology ((ALIM,volume 1))

Abstract

Mearns et al. (1) first reported an association between allergic bronchopulmonary aspergillosis (ABPA) and cystic fibrosis (CF) in 1965. Subsequently, other investigators have reported that ABPA occurs with an incidence of approx 10-11% in patients with CF(2-5). This is probably an underestimation because the underlying lung disease in patients with CF obscures many of the pulmonary findings considered cardinal signs of ABPA. However, distinguishing ABPA from infectious pulmonary disease in CF subjects is crucial for proper treatment. Untreated ABPA causes pulmonary inflammation, bron-chiectasis, and fibrosis.

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Knutsen, A.P., Slavin, R.G. (1990). Allergic Bronchopulmonary Aspergillosis in Patients with Cystic Fibrosis. In: Moss, R.B. (eds) Cystic Fibrosis. Allergy and Immunology, vol 1. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-4612-0475-6_7

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  • DOI: https://doi.org/10.1007/978-1-4612-0475-6_7

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4612-6778-2

  • Online ISBN: 978-1-4612-0475-6

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