Abstract
Trichoscopy of scalp lesions in pemphigus vulgaris and pemphigus foliaceous shows red, sharply demarcated, polygonal hemorrhagic areas; elongated serpentine blood vessels; dotted vessels with a whitish halo; large yellow dots with a whitish halo (“fried-egg sign”); and white lamellar structures. In pemphigoid, large yellow dots may be observed as well. Blisters and scarring features commonly are present. In dermatitis herpetiformis (Duhring’s disease), trichoscopy is characterized by clusters of dotted blood vessels.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Bystryn JC, Rudolph JL. Pemphigus. Lancet. 2005;366(9479):61–73.
Arya SR, Valand AG, Krishna K. A clinico-pathological study of 70 cases of pemphigus. Indian J Dermatol Venereol Leprol. 1999;65(4):168–71.
Esmaili N, Chams-Davatchi C, Valikhani M, Daneshpazhooh M, Balighi K, Hallaji Z, et al. Pemphigus vulgaris in Iran: a clinical study of 140 cases. Int J Dermatol. 2007;46(11):1166–70.
Salmanpour R, Shahkar H, Namazi MR, Rahman-Shenas MR. Epidemiology of pemphigus in south-western Iran: a 10-year retrospective study (1991–2000). Int J Dermatol. 2006;45(2):103–5.
Chams-Davatchi C, Valikhani M, Daneshpazhooh M, Esmaili N, Balighi K, Hallaji Z, et al. Pemphigus: analysis of 1209 cases. Int J Dermatol. 2005;44(6):470–6.
Veraitch O, Ohyama M, Yamagami J, Amagai M. Alopecia as a rare but distinct manifestation of pemphigus vulgaris. J Eur Acad Dermatol Venereol. 2011. doi:10.1111/j.1468-3083.2011.04363.x.
Sar-Pomian M, Kolacinska-Strasz Z, Labecka H, Krainska-Wojcik T, Olszewska M. Scalp lesions in pemphigus. Przegl Dermatol. 2010;97:14–20.
Lapiere K, Caers S, Lambert J. A case of long-lasting localized pemphigus vulgaris of the scalp. Dermatology. 2004;209(2):162–3.
Rackett SC, Rothe MJ, Hoss DM, Grin-Jorgensen CM, Grant-Kels JM. Treatment-resistant pemphigus vegetans of the scalp. Int J Dermatol. 1995;34(12):865–6.
Wilson CL, Dean D, Wojnarowska F. Pemphigus and the terminal hair follicle. J Cutan Pathol. 1991;18(6):428–31.
Ioannides D, Hytiroglou P, Phelps RG, Bystryn JC. Regional variation in the expression of pemphigus foliaceus, pemphigus erythematosus, and pemphigus vulgaris antigens in human skin. J Invest Dermatol. 1991;96(2):159–61.
Ball S, Walkden V, Wojnarowska F. Cicatricial pemphigoid rarely involves the scalp. Australas J Dermatol. 1998;39(4):258–60.
Fukuda S, Tsuruta D, Uchiyama M, Mitsuhashi Y, Kobayashi H, Ishikawa T, et al. Brunsting-Perry type pemphigoid with IgG autoantibodies to laminin-332, BP230 and desmoplakins I/II. Br J Dermatol. 2011;165(2):433–5.
Minato H, Ishii N, Fukuda S, Wakasa T, Wakasa K, Sogame R, et al. Heterogeneity of Brunsting-Perry type pemphigoid: a case showing blister formation at the lamina lucida, immune deposition beneath the lamina densa and autoantibodies against the 290-kD polypeptide along the lamina densa. J Dermatol. 2011;38(9):887–92.
Kneisel A, Hertl M. Autoimmune bullous skin diseases. Part 1: clinical manifestations. J Dtsch Dermatol Ges. 2011;9(10):844–956; quiz 857.
Miteva M, Murrell DF, Tosti A. Hair loss in autoimmune cutaneous bullous disorders. Dermatol Clin. 2011;29(3):503–9, xi.
Rose C, Brocker EB, Zillikens D. Clinical, histological and immunpathological findings in 32 patients with dermatitis herpetiformis Duhring. J Dtsch Dermatol Ges. 2010;8(4):265–70, 271.
Gul U, Soylu S, Heper AO. An unusual case of dermatitis herpetiformis presenting with initial scalp localization. Indian J Dermatol Venereol Leprol. 2009;75(6):620–2.
Kurzeja M, Rakowska A, Olszewska M, Rudnicka L.Trichoscopy (dermoscopy of the scalp) in autoimmune bullous skin diseases. Abstract CD. 21st Congres of the European Academy of Dermatology and Venereology, Prague 27-30.09.2012.
Koch PJ, Mahoney MG, Cotsarelis G, Rothenberger K, Lavker RM, Stanley JR. Desmoglein 3 anchors telogen hair in the follicle. J Cell Sci. 1998;111(Pt 17):2529–37.
Schaerer L, Trueb RM. Direct immunofluorescence of plucked hair in pemphigus. Arch Dermatol. 2003;139(2):228–9.
Kurzeja M, Rakowska A, Rudnicka L, Olszewska M. Criteria for diagnosing pemphigus vulgaris and pemphigus foliaceus by reflectance confocal microscopy. Skin Res Technol. 2012 Aug;18(3)339–46. doi:10.1111/j.1600-0846.2011.00574.x.
Delmonte S, Semino MT, Parodi A, Rebora A. Normal anagen effluvium: a sign of pemphigus vulgaris. Br J Dermatol. 2000;142(6):1244–5.
Koslu A, Topal IO, Ekmekci TR. Trichogram findings in pemphigus patients. Indian J Dermatol Venereol Leprol. 2009;75(3):303–4.
Saijyo S, Tagami H. Tufted hair folliculitis developing in a recalcitrant lesion of pemphigus vulgaris. J Am Acad Dermatol. 1998;38(5 Pt 2):857–9.
Petronić-Rosić V, Krunić A, Mijusković M, Vesić S. Tufted hair folliculitis: a pattern of scarring alopecia? J Am Acad Dermatol. 1999;41(1):112–4.
Jappe U, Schroder K, Zillikens D, Petzoldt D. Tufted hair folliculitis associated with pemphigus vulgaris. J Eur Acad Dermatol Venereol. 2003;17(2):223–6.
Kurzeja M Application of reflectance confocal microscopy in diagnosing pemphigus vulgaris and pemphigus foliaceus. PhD Thesis, Medical University of Warsaw, Warsaw 2013.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag London
About this chapter
Cite this chapter
Kurzeja, M., Olszewska, M., Rudnicka, L. (2012). Autoimmune Bullous Diseases. In: Rudnicka, L., Olszewska, M., Rakowska, A. (eds) Atlas of Trichoscopy. Springer, London. https://doi.org/10.1007/978-1-4471-4486-1_32
Download citation
DOI: https://doi.org/10.1007/978-1-4471-4486-1_32
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-4471-4485-4
Online ISBN: 978-1-4471-4486-1
eBook Packages: MedicineMedicine (R0)