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Dissolution of Stones by Oral and Irrigative Therapy

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Urolithiasis

Abstract

Advancement in percutaneous and endoscopic techniques has revolutionized surgical treatment options for upper and lower urinary tract calculi. However, while the use of oral and irrigative therapies for stone dissolution has declined over the last decades, these therapies continue to serve as a safe alternative to surgery, especially in patients with significant comorbidities. This chapter examines principles of chemolysis for component-specific stone dissolution including pH manipulation, cation chelation, and mixed disulfide bond formation, as well as setup and deployment of percutaneous irrigation systems.

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Author information

Authors and Affiliations

  1. Department of Urology, Columbia University College of Physicians and Surgeons, New York Presbyterian Hospital Kidney Stone Center, New York, NY, USA

    Ruslan Korets M.D. & Joseph A. Graversen M.D.

  2. Director of Endourology, Columbia University and NYPH Kidney Stone Center, New York, NY, USA

    Mantu Gupta M.D.

Authors
  1. Ruslan Korets M.D.
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  2. Joseph A. Graversen M.D.
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  3. Mantu Gupta M.D.
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Corresponding author

Correspondence to Mantu Gupta M.D. .

Editor information

Editors and Affiliations

  1. Department of Surgery Section of Urology, Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan

    Jamsheer J. Talati

  2. Karolinska Institutet, Solnavägen 1, Solna, Stockholm, 171 77, Sweden

    Hans-Goran Tiselius

  3. , Syracuse University, Crouse Hospital, 1226 East Water Street, New York, 13210, New York, USA

    David M. Albala

  4. , Department of Urology, Tongji Hospital, 1095 Jiefang Avenue, Wuhan, 430030, China, People's Republic

    ZHANGQUN YE

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© 2012 Springer-Verlag London

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Korets, R., Graversen, J.A., Gupta, M. (2012). Dissolution of Stones by Oral and Irrigative Therapy. In: Talati, J., Tiselius, HG., Albala, D., YE, Z. (eds) Urolithiasis. Springer, London. https://doi.org/10.1007/978-1-4471-4387-1_66

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  • DOI: https://doi.org/10.1007/978-1-4471-4387-1_66

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4383-3

  • Online ISBN: 978-1-4471-4387-1

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