Summary
We therefore believe that our therapeutic concept is a true alternative to primary cystectomy, with comparable survival rates. We observed a high rate of functional organ preservation in long-term survivors (79% with complete remission (CR) after 5 years). Radiation bladders were rare at doses not exceeding 60 Gy. Age and co-morbidity were not exclusion criteria. Presence of a competent and cooperative radiotherapy department is a precondition to preventing akinetic radiation bladders. Continuous life-long follow-up is necessary.2 Cystectomy, together with modern urinary diversions, is still necessary; it is performed in non-responders and in patients with muscle-invasive recurrences.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Blandy JP, England HR, Evans SJW et al: T3 bladder cancer: The case for salvage cystectomy. Br J Urol, 52:506, 1980.
Block T, Kriegmair M, Busch M, Weiss M: Harnblasenkarzinom. In Schmeller N, ed. Empfehlungen zur Diagnostik und Therapie und Nachsorge: Urogenitale Tumoren. Tumorzentrum München 1997.
Clavel J, Cordier S, Boccon - Gibod Lhemon D: Tobacco and bladder cancer in males. Increased risk for inhalers and smokers of black tobacco. Int J Cancer 44:605, 1984.
Dunst J, Sauer R, Schrott KM, Kühn R, Wittekind C, Altendorf-Hoffmann A: Organ Sparing Treatment of Advanced bladder cancer: A 10 year experience. Int J of Radiation Oncol Biol Phys, 30(2):261, 1994.
Göckcebay E, Riedmiller H, Stöckle M, Hohenfellner R: Urethrale Tumorrezidive nach Radikaler Zystoprostatektomie — Eine Indikation zur primären Zystoprostato-Urethrektomie? Urologe A, 28(4):199, 1989.
Hartenstein R: Harnblasenkarzinom. In: Huhn D, Herrmann R, eds. Medikamentöse Therapie maligner Erkrankungen. Fischer Verlag Stuttgart pp 364–373, 1995.
International union against cancer. In: Sobin LH, Wittekind C, eds. TNM classification of malignant tumours, 5th ed. New York: Wiley Liss, 1997.
Jensen OM, Estere J, Moller J, Renard H: Cancer in the European community and its member states. Eur J Cancer, 26:1167, 1990.
Mostofi FK, Sobin LH, Torloni H: Histological typing of urinary bladder tumours. International classification of tumours, No 10. WHO, Geneva 1973.
Norpoth K, Woitowitz HJ: Beruflich verursachte Tumoren, Detuscher Ärzteverlag Köln ISBN 3-7691-0304-1, 1994.
Kaufman DS, Shiplet NU, Henry NM: Invasive bladder carcinoma: Rationale for radiotherapy with potential bladder sparing. In: Fitzpatrick JM, ed. The bladder. New York: Churchill Livingstone, p. 351–539, 1995.
Ritchie JP, Shipley WU, Yagoda A: Cancer of the bladder. In: De Vita VT, Hellmann S, Rosenberg SA, eds. Cancer principles and practice of oncology. Philadelphia: J B Lipincott, p. 1008–1020, 1989.
Voges GE, Tauschke E, Stöckle M, Alken P, Hohenfellner R: Computerized tomography — an unreliable method for accurate staging of bladder tumours in patients who are candidates for radical cystectomy. J Urol, 142:972, 1989.
Yagoda A: Chemotherapy of urothelial tract tumors. Cancer, 60(Suppl):574, 1987.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer Science+Business Media New York
About this chapter
Cite this chapter
Brod, J.L., Kühn, R., Schafhauser, W., Schrott, K.M. (2003). Radiochemotherapy in Locally Invasive Non-Metastatic Carcinoma of the Bladder. In: Atala, A., Slade, D. (eds) Bladder Disease, Part A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8889-8_12
Download citation
DOI: https://doi.org/10.1007/978-1-4419-8889-8_12
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-4707-1
Online ISBN: 978-1-4419-8889-8
eBook Packages: Springer Book Archive