Skip to main content
SpringerLink
Log in
Book cover

Advances in TNF Family Research

Proceedings of the 12th International TNF Conference, 2009

  • Conference proceedings
  • © 2011

Overview

Editors:
  1. David Wallach

    1. Dept. Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Andrew Kovalenko

    1. Dept. Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. Marc Feldmann

    1. Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Most up-to-date book on current research of the TNF family
  • TNF meetings follow the enormous progress in this field
  • The conference focused on the physiological, pathophysiological, and medical significance of these important regulators
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 691)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 259.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (66 papers)

  1. Front Matter

    Pages i-xxxvi
    Download chapter PDF

  2. Roles of the TNF Family in Tissue Homeostasis and Normal Development

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Workshop Summary: Roles of the TNF Family in Normal Development and Cancer

      • Nancy H. Ruddle
      Pages 3-4

    3. TNF Conference 2009: Beyond Bones – RANKL/RANK in the Immune System

      • Andreas Leibbrandt, Josef M. Penninger
      Pages 5-22

    4. The Edar Subfamily in Hair and Exocrine Gland Development

      • Marja L. Mikkola
      Pages 23-33

    5. High Endothelial Venule Reporter Mice to Probe Regulation of Lymph Node Vasculature

      • Kevin L. Bentley, Sharon Stranford, Shan Liao, Rawad M. Mounzer, Frank H. Ruddle, Nancy H. Ruddle
      Pages 35-44

    6. Eiger and Wengen: The Drosophila Orthologs of TNF/TNFR

      • Tatsushi Igaki, Hiroshi Kanda, Hideyuki Okano, Tian Xu, Masayuki Miura
      Pages 45-50

  3. Novel Aspects of Signaling Activation by the TNF Family: Novel Aspects of the Functions of the TRAFs and cIAPs

    1. Front Matter

      Pages 51-51
      Download chapter PDF

  4. Novel Aspects of Signaling Activation by the TNF Family: Novel Aspects of the Functions of the TRAFs and cIAPs

    1. Workshop Summary: Novel Aspects of the Functions of the TRAFs and cIAPs

      • John Silke, Domagoj Vucic
      Pages 53-61

    2. TRAF2 and Cellular IAPs: A Critical Link in TNFR Family Signaling

      • Domagoj Vucic
      Pages 63-78

    3. New Perspectives in TNF-R1-Induced NF-κB Signaling

      • Ian E. Gentle, John Silke
      Pages 79-88

    4. Structural Studies of NEMO and TRAF6: Implications in NF-κB Activation

      • Hao Wu, Yu-Chih Lo, Qian Yin
      Pages 89-91

  5. Novel Aspects of Signaling Activation by the TNF: Ubiquitin Modification of Signaling Proteins

    1. Front Matter

      Pages 93-93
      Download chapter PDF

  6. Novel Aspects of Signaling Activation by the TNF : Ubiquitin-Modification of Signaling Proteins

    1. Modification by Single Ubiquitin Moieties Rather Than Polyubiquitination Is Sufficient for Proteasomal Processing of the p105 NF-κB Precursor

      • Yelena Kravtsova-Ivantsiv, Shai Cohen, Aaron Ciechanover
      Pages 95-106

    2. Selective Binding of Linear Ubiquitin Chains to NEMO in NF-kappaB Activation

      • Fumiyo Ikeda, Simin Rahighi, Soichi Wakatsuki, Ivan Dikic
      Pages 107-114

    3. The Linear Ubiquitin Chain Assembly Complex (LUBAC) Forms Part of the TNF-R1 Signalling Complex and Is Required for Effective TNF-Induced Gene Induction and Prevents TNF-Induced Apoptosis

      • Christoph H. Emmerich, Anna C. Schmukle, Tobias L. Haas, Björn Gerlach, Stefanie M. Cordier, Eva Rieser et al.
      Pages 115-126

    4. Temporal Control of TNFα Signaling by Miz1

      • Anning Lin
      Pages 127-128

  7. Novel aspects of Signaling Activation by the TNF Family: TNF Signaling and Gene Regulatory Networks

    1. Front Matter

      Pages 129-129
      Download chapter PDF

  8. Novel aspects of Signaling Activation by the TNF Family: TNF Signaling- and gene Regulatory-Networks

    1. Large-Scale RNAi Screens to Dissect TNF and NF-κB Signaling Pathways

      • Marie Metzig, Dorothee Nickles, Michael Boutros
      Pages 131-139

    2. Pathogenic Role of IL-6 Combined with TNF-α or IL-1 in the Induction of Acute Phase Proteins SAA and CRP in Chronic Inflammatory Diseases

      • Kazuyuki Yoshizaki
      Pages 141-150
Back to top

About this book

The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, held in April 2009. This conference focuses on the physiological, pathophysiological, and medical significance of these important regulators. Sessions at the meeting specifically address their involvement in immunity, development, apoptosis, autoimmunity, cancer, and infection, the normal function and pathology of the neuronal system, as well as major unresolved questions about their mechanisms of action.

Editors and Affiliations

  • Dept. Biological Chemistry, Weizmann Institute of Science, Rehovot, Israel

    David Wallach, Andrew Kovalenko

  • Kennedy Institute of Rheumatology, Imperial College London, London, United Kingdom

    Marc Feldmann

Bibliographic Information

  • Book Title: Advances in TNF Family Research

  • Book Subtitle: Proceedings of the 12th International TNF Conference, 2009

  • Editors: David Wallach, Andrew Kovalenko, Marc Feldmann

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4419-6612-4

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2011

  • Hardcover ISBN: 978-1-4419-6611-7Published: 10 December 2010

  • Softcover ISBN: 978-1-4614-2783-4Published: 31 January 2013

  • eBook ISBN: 978-1-4419-6612-4Published: 09 December 2010

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XXXVI, 844

  • Topics: Immunology, Microbiology, Biomedicine general

Publish with us

Policies and ethics

Back to top

Search

Navigation