Abstract
Thrombectomy devices have been developed as an alternative means for clot removal. A number of devices using a variety of methods to remove the clot are now available. This chapter covers the analysis and research into a device recently developed in the UK, called a “GP” thrombus aspiration device (TAD). Presented in this work is the development of a model of this device, as well as its simulation and interpretation of the results obtained with the potential for helping in optimizing its operation for future use. The simulation model that is presented can be used in showing the potential performance of the “GP” TAD device under different conditions of blood flow and size of blood clot, obtaining the minimum pressure necessary to extract the clot and to check that both this pressure and the time required to complete the operation are reasonable for potential use in clinical situations patients, and are in line with experimentally obtained data.
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References
Stroke association website: http://www.stroke.org.uk/document.rm?id=330. Last accessed 30 December 2008.
Broderick JP (2008). Endovascular therapy for acute ischemic stroke. Stroke 40:103–106.
Thomassen L, Bakke SJ (2007). Endovascular reperfusion therapy in acute ischaemic stroke. Acta Neurol Scand Suppl 187:22–29.
Rothwell PM, Eliasziw M, Gutnikov SA, Warlow CP, Barnett HJM (2004). Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. Lancet 363:915–924.
Pearce G, Perkinson ND (2006). “Biomechanical Probe”. International Patent Corporate Treatise (WO2006120464) published 2006-11-16; European patent (EP1893195 (A2)) published 2008-03-05; Japanese patent (JP2008639924 (T)) published 2008-11-20; Chinese patent (CN101208049 (A)) published 2008-06-25.
Pearce G, Patrick JH, Perkinson ND (2007). A new device for the treatment of thromboembolic strokes. J Stroke Cerebrovasc Dis 16(4):167–172.
Pearce G, Jaegle F, Gwatkin L, Wong J, Perkinson ND, Spence J (2009). An investigation of fluid flow through a modified design for the ‘GP’ device. 11th International Conference on Computer Modelling and Simulation, Cambridge, UK, pp. 191–195.
Karnopp DC, Margolis DL, Rosemberg RC (1990). System dynamics: A unified approach, 2nd edition. Wiley, New York.
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Romero, G. et al. (2010). Computational Modeling of a New Thrombectomy Device for the Extraction of Blood Clots. In: Arabnia, H. (eds) Advances in Computational Biology. Advances in Experimental Medicine and Biology, vol 680. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5913-3_69
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DOI: https://doi.org/10.1007/978-1-4419-5913-3_69
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