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Liquid Biopsy, a Potential New Detection Method in Heart Allograft Rejection

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Liquid Biopsies

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2695))

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Abstract

Allografts rejection remains the most important reason causing allograft dysfunction in heart transplantation recipients. Currently, the golden standard for detecting graft rejection is endomyocardial biopsy (EMB). As a new noninvasive technique, liquid biopsy emerges along with the great developments of droplet-based digital PCR and the various optimizations of next-generation sequencing technologies, which is also cheaper than EMB. This review introduces several types of liquid biopsy and its application in heart transplantation.

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Author information

Authors and Affiliations

  1. Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

    Chenghao Li & Guohua Wang

Authors
  1. Chenghao Li
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  2. Guohua Wang
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Corresponding author

Correspondence to Guohua Wang .

Editor information

Editors and Affiliations

  1. CAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai, China

    Tao Huang

  2. Geneis Beijing Co. Ltd., Beijing, China

    Jialiang Yang

  3. Geneis Beijing Co. Ltd., Beijing, China

    Geng Tian

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© 2023 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Li, C., Wang, G. (2023). Liquid Biopsy, a Potential New Detection Method in Heart Allograft Rejection. In: Huang, T., Yang, J., Tian, G. (eds) Liquid Biopsies. Methods in Molecular Biology, vol 2695. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3346-5_21

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  • DOI: https://doi.org/10.1007/978-1-0716-3346-5_21

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3345-8

  • Online ISBN: 978-1-0716-3346-5

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