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Animal Models of COVID-19: Nonhuman Primates

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SARS-CoV-2

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2452))

Abstract

With the advent of the novel SARS-CoV-2, the entire world has been thrown into chaos with severe disruptions from a normal life. While the entire world was going chaotic, the researchers throughout the world were struggling to contribute to the best of their capabilities to advance the understanding of this new pandemic and fast track the development of novel therapeutics and vaccines. While various animal models have helped a lot to understand the basic physiology, nonhman primates have been promising and much more successful in modelling human diseases compared to other available clinical models. Here we describe the different aspects of modelling the SARS-CoV-2 infection in NHPs along with the associated methods used in NHP immunology.

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Author information

Authors and Affiliations

  1. Southwest National Primate Research Center, San Antonio, TX, USA

    Dhiraj K. Singh, Journey Cole, Ruby A. Escobedo, Bindu Singh, Tae-Hyung Lee, Xavier Alvarez, Shashank R. Ganatra & Deepak Kaushal

  2. Texas Biomedical Research Institute, San Antonio, TX, USA

    Dhiraj K. Singh, Journey Cole, Ruby A. Escobedo, Kendra J. Alfson, Bindu Singh, Tae-Hyung Lee, Xavier Alvarez, Shashank R. Ganatra, Ricardo Carrion, Jr & Deepak Kaushal

Authors
  1. Dhiraj K. Singh
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  2. Journey Cole
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  3. Ruby A. Escobedo
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  4. Kendra J. Alfson
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  5. Bindu Singh
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  6. Tae-Hyung Lee
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  7. Xavier Alvarez
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  8. Shashank R. Ganatra
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  9. Ricardo Carrion, Jr
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  10. Deepak Kaushal
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Corresponding author

Correspondence to Deepak Kaushal .

Editor information

Editors and Affiliations

  1. Department of Microbiology and Immunology; Infectious Disease TRD; BSL3 Core Facility, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

    Justin Jang Hann Chu

  2. The University of British Columbia, Vancouver, BC, Canada

    Bintou Ahmadou Ahidjo

  3. BSL3 Core Facility, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

    Chee Keng Mok

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© 2022 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Singh, D.K. et al. (2022). Animal Models of COVID-19: Nonhuman Primates. In: Chu, J.J.H., Ahidjo, B.A., Mok, C.K. (eds) SARS-CoV-2. Methods in Molecular Biology, vol 2452. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2111-0_15

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  • DOI: https://doi.org/10.1007/978-1-0716-2111-0_15

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-2110-3

  • Online ISBN: 978-1-0716-2111-0

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