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Topology Results on Adjacent Amino Acid Networks of Oligomeric Proteins

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Allostery

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2253))

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Abstract

In this chapter, we focus on topology measurements of the adjacent amino acid networks for a data set of oligomeric proteins and some of its subnetworks. The aim is to present many mathematical tools in order to understand the structures of proteins implicitly coded in such networks and subnetworks. We mainly investigate four important networks by computing the number of connected components, the degree distribution, and assortativity measures. We compare each result in order to prove that the four networks have quite independent topologies.

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Acknowledgement

The authors would like to thank the CNRS and the MITI for the support within the project 80|Prime.

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Authors and Affiliations

  1. Institut Rhônalpin des systèmes complexes, IXXI-ENS-Lyon, Lyon, France

    Claire Lesieur

  2. AMPERE, CNRS, Univ. Lyon, Lyon, France

    Claire Lesieur

  3. LAMA, Univ. Savoie Mont Blanc, CNRS, LAMA, Le Bourget du Lac, France

    Laurent Vuillon

Authors
  1. Claire Lesieur
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  2. Laurent Vuillon
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Corresponding author

Correspondence to Laurent Vuillon .

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Editors and Affiliations

  1. Unit of Chemical-Physics Fundamentals in Chemical Engineering Department of Engineering, Universitá Campus Bio-Medico di Rome, Rome, Italy

    Luisa Di Paola

  2. Environment and Health Department, Instituto Superiore di Sanità, Rome, Italy

    Alessandro Giuliani

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Lesieur, C., Vuillon, L. (2021). Topology Results on Adjacent Amino Acid Networks of Oligomeric Proteins. In: Di Paola, L., Giuliani, A. (eds) Allostery. Methods in Molecular Biology, vol 2253. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1154-8_8

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  • DOI: https://doi.org/10.1007/978-1-0716-1154-8_8

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1153-1

  • Online ISBN: 978-1-0716-1154-8

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