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Antibody Printing Technologies

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Antibody Arrays

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2237))

Abstract

Antibody microarrays are routinely employed in the lab and in the clinic for studying protein expression, protein-protein, and protein-drug interactions. The microarray format reduces the size scale at which biological and biochemical interactions occur, leading to large reductions in reagent consumption and handling times while increasing overall experimental throughput. Specifically, antibody microarrays, as a platform, offer a number of different advantages over traditional techniques in the areas of drug discovery and diagnostics. While a number of different techniques and approaches have been developed for creating micro and nanoscale antibody arrays, issues relating to sensitivity, cost, and reproducibility persist. The aim of this review is to highlight current state-of the-art techniques and approaches for creating antibody arrays by providing latest accounts of the field while discussing potential future directions.

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Authors and Affiliations

  1. Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia

    Valentin Romanov

  2. Biomedical Sciences, Rocky Vista University, Ivins, UT, USA

    Benjamin D. Brooks

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  1. Valentin Romanov
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Correspondence to Valentin Romanov .

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  1. RayBiotech, Peachtree Corners, GA, USA

    Kelly C. Whittaker

  2. RayBiotech Life, Peachtree Corners, GA, USA

    Ruo-Pan Huang

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Romanov, V., Brooks, B.D. (2021). Antibody Printing Technologies. In: Whittaker, K.C., Huang, RP. (eds) Antibody Arrays. Methods in Molecular Biology, vol 2237. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1064-0_13

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  • DOI: https://doi.org/10.1007/978-1-0716-1064-0_13

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