Acquired coagulation abnormalities are not infrequently detected in the laboratory evaluation of patients with paraproteinemias; however, clinically evident manifestations are observed in only 10% of such patients [1]. The hemorrhages observed with these abnormalities are rarely spontaneous, but often associated with surgical procedures. Hemostatic abnormalities have been reported in patients with primary AL amyloidosis, Waldenström macroglobulinemia, multiple myeloma and monoclonal gammopathy of undetermined significance (MGUS).
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Zangari, M., Elice, F., Tricot, G., Fink, L. (2009). Bleeding Disorders Associated with Cancer Dysproteinemias. In: Kwaan, H., Green, D. (eds) Coagulation in Cancer. Cancer Treatment and Research, vol 148. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-79962-9_17
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