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References
Griffiths AM. Specificities of inflammatory bowel disease. Best Pract & Res Clin Gastroenterol 2004;18:509–523.
Carvalho RS, Abandom V, Dilworth HP, et al. Indeterminate colitis:a significant subgroup of pediatric IBD. Inflamm Bowel Dis 2006;12:258–262.
Griffiths AM, Otley AR, Hyams J. et al. A review of activity indices and end points for clinical trials in children with Crohn disease. Inflamm Bowel Dis 2005;11:185–196.
Sands BE, Abreu MT, Ferry G et al. Design issues and outcomes in IBD clinical trials. Inflamm Bowel Dis 2005;11:S22–S28.
Pappa HM, Semrin G, Walker TR, Grand RJ. Pediatric inflammatory bowel disease. Curr Opin Gastroenterol 2004;20:333–340.
Crofton PM, Kelnar CJH. Bone and collagen markers in pediatric practice. Int J Clin Pract 1998;52: 557–565.
Kim SC, Ferry GD. Inflammatory bowel disease in early childhood and adolescence: special considerations. Gastroenterology 2004;126:1550–1560.
Best W, Becktel J, Singleton J et al. Development of a Crohn disease activity index. Gastroenterology 1976;70:439–444.
Hyams J, Ferry G, Mandel F, et al. Development and validation of a pediatric Crohn disease activity index. J Pediatr Gastroenterol Nutr 1991;12:439–447.
Kundhal PS, Critch JN, Zachos M, et al. Pediatric Crohn disease activity index:responsive to short-term change. J Pediatr Gastroenterol Nutr 2003;36:83–89.
Otley A, Loonen H, Parekh N, et al. Assessing activity of pediatric Crohn disease:which index to use? Gastroenterology 1999;116:527–531.
Hyams J, Markowitz J, Otley A, et al. Evaluation of the pediatric Crohn disease activity index: usefulness in the practice setting. J Pediatr Gastroenterol Nutr 2004;39 (Suppl):0712.
Hyams J, Markowitz J, Otley A, et al. Evaluation of the pediatric Crohn disease activity index:a prospective multicenter experience. J Pediatr Gastroenterol Nutr 2005;41:416–421.
Truelove SC, Witts LJ. Cortisone in ulcerative colitis. Final report on a therapeutic trial. BMJ 1955;2:1041–8.
Powell-Tuck J, Bown RL, Lennard-Jones JE. A comparison of oral prednisone given as single or multiple daily doses for active ulcerative colitis. Scand J Gastroenterol 1978;13:833–7.
Rachmilewitz D. Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in treatment of active ulcerative colitis: a randomised trial. BMJ 1989;298:82–6.
Baron JH, Conell AM, Lennard-Jones JE. Variation between observers in describing mucosal appearance in proctocolitis. BMJ 1964;1:89–92.
Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderate active ulcerative colitis. A randomised study. N Engl J Med 1987;317:1625–9.
D’Haens G, Hlavaty T. Advances in medical therapy for Crohn disease. Curr Gastroenterol Rep 2004;6:496–505.
Mamula P, Markowitz JE, Baldassano RN. Inflammatory bowel disease in early childhood and adolescence: special considerations. Gastroenterol Clin North Am 2003;32:867–995.
Arnott ID, Watts D, Ghosh S. Review article:is clinical remission the optimum therapeutic goal in the treatment of Crohn disease? Aliment Pharmacol Ther 2002;16:857–67.
Rutgeerts P, Diamond RH, Bala M, et al. Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn disease. Gastrointest Endosc 2006;63:433–442.
Griffiths AM, Nicholas D, Smith C, et al. Development of a quality-of-life index for pediatric inflammatory bowel disease: dealing with differences related to age and IBD type. J Pediatr Gastroenterol Nutr 1999;28:S46–S52.
Otley A, Smith C, Nicholas D, et al. The IMPACT questionnaire: a valid measure of health-related quality of life in pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2002;35:557–563.
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Cucchiara, S., Borrelli, O. (2008). Clinical Trials (Clinical Perspective). In: Mamula, P., Markowitz, J.E., Baldassano, R.N. (eds) Pediatric Inflammatory Bowel Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-73481-1_40
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DOI: https://doi.org/10.1007/978-0-387-73481-1_40
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