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Model Systems for Studying Polyvalent Carbohydrate Binding Interactions

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Host-Guest Chemistry

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 218))

Abstract

This chapter describes several classes of model systems that have been used for studies of polyvalent binding interactions between carbohydrates and proteins. This review is divided into two parts. The first section provides a mechanistic analysis of polyvalent recognition. The second section utilizes this mechanistic framework to describe and analyze several major classes of model systems. The description of each model system is accompanied by a summary of recent experimental results from the literature. The chapter concludes with a comparison of the model systems and an introduction to several novel model systems that promise to broaden the scope of future studies in polyvalent carbohydrate-protein interactions.

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  1. Department of Chemistry, The University of Chicago, Chicago, IL, 60637, USA

    Benjamin T. Houseman & Milan Mrksich

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  1. Benjamin T. Houseman
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  1. Instituto de Investigaciones Químicas, Consejo Superior Investigaciones Cientificas, CSIC, Isla de la Cartuja, 41092, Sevilla, Spain

    Soledad Penadés

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Houseman, B.T., Mrksich, M. (2002). Model Systems for Studying Polyvalent Carbohydrate Binding Interactions. In: Penadés, S. (eds) Host-Guest Chemistry. Topics in Current Chemistry, vol 218. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45010-6_1

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