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Organization of the Adult Primate Fovea

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Macular Degeneration

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References

  • Ahnelt P, Kolb H (2000) The mammalian photoreceptor mosaic-adaptive design. Prog Retina Eye Res 19: 711–777

    CAS  Google Scholar 

  • Ahnelt P, Keri C, Kolb H (1990) Identification of pedicles of putative blue-sensitive cones in the human retina. J Comp Neurol 293: 39–53

    Article  PubMed  CAS  Google Scholar 

  • Barbosa-Carneiro L, Peret M, Bichara A, Coscarelli G, Peret P (2000) Isolated foveal hypoplasia. Invest Ophthalmol Vis Sci 41: S571

    Google Scholar 

  • Bird AC (2003) The Bowman Lecture. Towards an understanding of age-related macular disease. Eye 17: 457–466

    Article  PubMed  CAS  Google Scholar 

  • Borwein B, Borwein D, Medeiros J, McGowan JW (1980) The ultrastructure of monkey foveal photoreceptors, with special reference to the structure, shape, size and spacing of the foveal cones. Am J Anat 159: 125–146

    Article  PubMed  CAS  Google Scholar 

  • Boycott BB, Dowling JE (1969) Organization of the primate retina: light microscopy. Philos Trans R Soc Lond B Biol Sci 255: 109–184

    Google Scholar 

  • Bumsted K, Hendrickson A (1999) Distribution and development of short-wavelength cones differ between Macaca monkey and human fovea. J Comp Neurol 403: 502–516

    Article  PubMed  CAS  Google Scholar 

  • Bumsted K, Jasoni CL, Szél A, Hendrickson A (1997) Spatial and temporal expression of cone opsins during monkey retinal development. J Comp Neurol 378: 117–134

    Article  PubMed  CAS  Google Scholar 

  • Bumsted-O’Brien K, Schulte D, Hendrickson A (2003) Expression of photoreceptor-associated molecules during human fetal eye development. Mol Vis 9: 401–409

    Google Scholar 

  • Burris C, Klug K, Ngo IT, Sterling P, Schein S (2002) How Müller glial cells in macaque fovea coat and isolate the synaptic terminals of cone photoreceptors. J Comp Neurol 453: 100–111

    Article  PubMed  Google Scholar 

  • Cajal S Ramon Y (1892) La rétine des vertébrés. Cellule 9: 121–255

    Google Scholar 

  • Calkins DJ (2001) Seeing with S cones. Prog Retin Eye Res 20: 255–287

    Article  PubMed  CAS  Google Scholar 

  • Carroll J, Neitz J, Neitz M (2002) Estimates of L: M cone ratio from ERG flicker photometry and genetics. J Vis 2: 531–542

    PubMed  Google Scholar 

  • Chan-Ling T (1994) Glial, neuronal and vascular interactions in the mammalian retina. Prog Retin Eye Res 13: 357–389

    Article  Google Scholar 

  • Chun M-H, Grünert U, Martin PR, Wässle H (1996) The synaptic complex for cones in the fovea and in the periphery of the macaque monkey retina. Vis Res 36: 3383–3395

    PubMed  CAS  Google Scholar 

  • Curcio CA, Allen KA (1990) Topography of ganglion cells in human retina. J Comp Neurol 300: 5–25

    Article  PubMed  CAS  Google Scholar 

  • Curcio CA, Hendrickson AE (1991) Organization and development of the primate photoreceptor mosaic. Prog Retin Res 10: 89–120

    Google Scholar 

  • Curcio CA, Sloan KR, Kalina RE, Hendrickson AE (1990) Human photoreceptor topography. J Comp Neurol 292: 497–523

    Article  PubMed  CAS  Google Scholar 

  • Curcio CA, Allen KA, Sloan KR, Lerea CL, Hurley JB, Klock IB, Milam AH (1991) Distribution and morphology of human cone photoreceptors stained with anti-blue opsin. J Comp Neurol 312: 610–624

    Article  PubMed  CAS  Google Scholar 

  • Dacey DM (1999) Primate retina: cell types, circuits and color opponency. Prog Retin Eye Res 18: 737–763

    Article  PubMed  CAS  Google Scholar 

  • Deeb SS, Diller LC, Williams DR, Dacey DM (2000) Interindividual and topographical variation of L:M cone ratios in monkey retinas. J Opt Soc Am A Opt Imag Sci Vis 17: 538–544

    CAS  Google Scholar 

  • Delori FC, Goger DG, Hammond BR, Snodderly DM, Burns SA (2001) Macular pigment density measured by autofluorescence spectrometry: comparison with reflectometry and heterochromatic flicker photometry. J Opt Soc Am A Opt Imag Sci Vis 18: 1212–1230

    CAS  Google Scholar 

  • Distler C, Dreher Z (1996) Glia cells of the monkey retina. II. Müller cells. Vis Res 36: 2381–2394

    PubMed  CAS  Google Scholar 

  • Distler C, Kirby MA (1996) Transience of astrocytes in the newborn macaque monkey retina. Eur J Neurosci 8: 847–851

    PubMed  CAS  Google Scholar 

  • Distler C, Weigel H, Hoffman K-P (1993) Glia cells of the monkey retina. I. Astrocytes. J Comp Neurol 333: 134–147

    Article  PubMed  CAS  Google Scholar 

  • Distler C, Kopatz K, Telkes I (2000) Developmental changes in astrocyte density in the macaque perifoveal region. Eur J Neurosci 12: 1331–1341

    Article  PubMed  CAS  Google Scholar 

  • Dowling JE (1965) Foveal receptors of the monkey retina: fine structure. Science 147: 57–59

    PubMed  CAS  Google Scholar 

  • Engerman RL (1976) Development of the macular circulation. Invest Ophthalmol 15: 835–840

    PubMed  CAS  Google Scholar 

  • Fischer AJ, Reh TA (2003) Potential of Muller glia to become neurogenic retinal progenitor cells. Glia 43: 70–76

    Article  PubMed  Google Scholar 

  • Franco ECS, Finlay BL, Silveira LCL, Yamada ES, Crowley JC (2000) Conservation of absolute foveal area in New World monkeys. A constraint on eye size and conformation. Brain Behav Evol 56: 276–286.

    Article  PubMed  CAS  Google Scholar 

  • Fukada Y, Sawai H, Watanabe M, Wakakuwa K, Morigiwa K (1989) Nasotemporal overlap of crossed and uncrossed retinal ganglion cell projections in the Japanese monkey (Macaca fuscata). J Neurosci 9: 2353–2373

    Google Scholar 

  • Fulton AB, Albert DM, Craft JL (1978) Human albinism: light and electron microscopy. Arch Ophthalmol 96: 305–310

    PubMed  CAS  Google Scholar 

  • Gariano RF, Iruela-Arispe ML, Hendrickson AE (1994) Vascular development in primate retina: comparison of laminar plexus formation in monkey and human. Invest Ophthalmol Vis Sci 35: 3442–3455

    PubMed  CAS  Google Scholar 

  • Gariano RF, Iruela-Arispe ML, Sage EH, Hendrickson AE (1996a) Immunohistochemical characterization of developing and mature primate retinal blood vessels. Invest Ophthalmol Vis Sci 37: 93–103

    PubMed  CAS  Google Scholar 

  • Gariano RF, Sage EH, Kaplan HJ, Hendrickson AE (1996b) Development of astrocytes and their relation to blood vessels in fetal monkey retina. Invest Ophthalmol Vis Sci 37: 2367–2375

    PubMed  CAS  Google Scholar 

  • Goldberg ME (2000) The control of gaze. In: Kandel ER, Schwartz JH, Jessell TM (eds) Principles of neural science, 4th edn. McGraw-Hill, New York, pp 782–800

    Google Scholar 

  • Hagstrom SA, Neitz J, Neitz M (1998) Variations in cone populations for red-green color vision examined by analysis of mRNA. Neuroreport 9: 1963–1967

    PubMed  CAS  Google Scholar 

  • Haverkamp S, Grünert U, Wässle H (2000) The cone pedicle, a complex synapse in the retina. Neuron 27: 85–95

    Article  PubMed  CAS  Google Scholar 

  • Helmholtz H (1924) Treatise on physiological optics, the sensation of vision (JPC Southall, translator). Optical Society of America

    Google Scholar 

  • Hendrickson A (1992) A morphological comparison of foveal development in man and monkey. Eye 6: 136–144

    PubMed  Google Scholar 

  • Hendrickson A, Djajadi HR, Nakaura L, Possin DE, Sajuthi D (2000) Nocturnal tarsier retina has both short and long/medium-wavelength cones in an unusual topography. J Comp Neurol 424: 718–730

    Article  PubMed  CAS  Google Scholar 

  • Hogan, MJ, Alvarado JA, Weddell JE (1971) Histology of the Human Eye. Saunders, Philadelphia

    Google Scholar 

  • Hollyfield JG, Rayborn ME, Nihiyama K, Shadrach KG, Miyagi M, Crabb JW, Rodriquez IR (2001) Interphotoreceptor matrix in the fovea and peripheral retina of the primate Macaca mulatta; distribution and glyoforms of SPACR and SPACRCAN. Exp Eye Res 72: 49–61

    PubMed  CAS  Google Scholar 

  • Iwasaki M, Inomata H (1986) Relation between superficial capillaries and foveal structures in the human retina. Invest Ophthalmol Vis Sci 27: 1698–1705

    PubMed  CAS  Google Scholar 

  • Jacobs GH (1998) Photopigments and seeing — lessons from natural experiments. Invest Ophthalmol Vis Sci 39: 2205–2216

    Google Scholar 

  • Kolb H (1970) Organization of the outer plexiform layer of the primate retina: electron microscopy of Golgi-impregnated cells. Philos Trans R Soc London B Biol Sci 258: 261–283

    Google Scholar 

  • Kolb H (1994) The architecture of functional neural circuits in the vertebrate retina. The Proctor Lecture 1994. Invest Ophthalmol Vis Sci 35: 2385–404.

    PubMed  CAS  Google Scholar 

  • Krebs W, Krebs IP (1989) Quantitative morphology of the central fovea in the primate retina. Am J Anat 184: 225–236

    Article  PubMed  CAS  Google Scholar 

  • Krebs W, Krebs I (1991) Primate retina and choroid: atlas of fine structure in man and monkey. Springer-Verlag, New York

    Google Scholar 

  • Kremers J, Silveira LCL, Yamada ES, Lee BB (1999) The ecology and evolution of primate color vision. In: Gegenfurtner KR, Sharpe LT (eds) Color vision: from genes to perception. Cambridge University Press, Cambridge, UK, pp 123–142

    Google Scholar 

  • Mansour AM, Schachat A, Bodiford G, Haymond R (1993) Foveal avascular zone in diabetes mellitus. Retina 13: 125–128

    PubMed  CAS  Google Scholar 

  • Martin PR (1998) Colour processing in the primate retina: recent progress. J Physiol (Lond) 513: 631–638

    Article  PubMed  CAS  Google Scholar 

  • Martin PR, Grünert U (1999) Analysis of the short wavelength-sensitive “blue” cone mosaic in the primate retina: comparison of new world and old world monkeys. J Comp Neurol 406: 1–14

    Article  PubMed  CAS  Google Scholar 

  • Martin PR, Grünert U, Chan TL, Bumsted K (2000) Spatial order in short-wavelength-sensitive cone photoreceptors: a comparative study of the primate retina. J Opt Soc Am A Opt Imag Sci Vis 17: 557–567

    CAS  Google Scholar 

  • Martin PR, Lee BB, White AJ, Solomon SG, Ruttiger L (2001) Chromatic sensitivity of ganglion cells in the peripheral primate retina. Nature 410: 933–936

    Article  PubMed  CAS  Google Scholar 

  • McMahon C, Neitz J, Dacey DM, Neitz M (2001) Reversed L:M cone ratio in baboon indicates that pigment gene order does not determine relative cone number. Invest Ophthalmol Vis Sci 44: 72S

    Google Scholar 

  • Mietz H, Green WR, Wolff SM, Abundo GP (1992) Foveal hypoplasia in complete oculocutaneous albinism. Retina 12: 254–260

    PubMed  CAS  Google Scholar 

  • Milam AH, Li ZY, Fariss RN (1998) Histopathology of the human retina in retinitis pigmentosa. Prog Retin Eye Res 17: 175–205

    PubMed  CAS  Google Scholar 

  • Missotten L (1965) The ultrastructure of the human retina. Arsia, Brussels, Belgium

    Google Scholar 

  • Missotten L (1974) Estimation of the ratio of the cones and neurons in the fovea of the human retina. Invest Ophthalmol 13: 1045–1049

    PubMed  CAS  Google Scholar 

  • Mollon JD, Bowmaker JK (1992) The spatial arrangement of cones in the primate fovea. Nature 360: 677–679

    Article  PubMed  CAS  Google Scholar 

  • Nathans J, Thomas D, Hogness DS (1986) Molecular genetics of human color vision: the genes encoding blue, green and red pigments. Science 232: 193–202

    PubMed  CAS  Google Scholar 

  • Oliver MD, Dotan SA, Chemke J, Abraham FA (1987) Isolated foveal hypoplasia. Br J Ophthalmol 71: 926–930

    PubMed  CAS  Google Scholar 

  • Osterberg G (1935) Topography of the layer of rods and cones in the human retina. Acta Ophthalmol [Suppl VI]: 1–102

    Google Scholar 

  • Packer O, Hendrickson AE, Curcio CA (1989) Photoreceptor topography of the retina in the adult pigtail macaque (Macaca nemestrina). J Comp Neurol 288: 165–183

    Article  PubMed  CAS  Google Scholar 

  • Packer OS, Williams DR, Bensinger DG (1996) Photopigment transmittance imaging of the primate photoreceptor mosaic. J Neurosci 16: 2251–2260

    PubMed  CAS  Google Scholar 

  • Panda-Jones S, Jonas JB, Jakobczyk-Zmija M (1996) Retinal pigment epithelial cell count, distribution and correlations in normal human eyes. Am J Ophthalmol 121: 181–189

    Google Scholar 

  • Penfold PL, Madigan MC, Gillies MC, Provis JM (2001) Immunological and aetiological aspects of macular degeneration. Prog Retin Eye Res 20: 385–414

    Article  PubMed  CAS  Google Scholar 

  • Polyak SL (1941) The retina. University of Chicago Press, Chicago, IL

    Google Scholar 

  • Provis JM (2001) Development of the primate retinal vasculature. Prog Retin Eye Res 20: 799–821

    Article  PubMed  CAS  Google Scholar 

  • Provis JM, Diaz CM, Penfold PL (1996) Microglia in human retina: a heterogeneous population with distinct ontogenies. Perspect Dev Neurobiol 3: 213–221

    PubMed  CAS  Google Scholar 

  • Provis JM, Leech J, Diaz CM, Penfold PL, Stone J, Keshet E (1997) Development of the human retinal vasculature: cellular relations and VEGF expression. Exp Eye Res 65: 555–568

    Article  PubMed  CAS  Google Scholar 

  • Provis JM, Diaz CM, Dreher B (1998) Ontogeny of the primate fovea: a central issue in retinal development. Prog Neurobiol 54: 549–580

    Article  PubMed  CAS  Google Scholar 

  • Provis JM, Sandercoe T, Hendrickson AE (2000) Astrocytes and blood vessels define the foveal rim during primate retinal development. Invest Ophthalmol Vis Sci 41: 2827–2836

    PubMed  CAS  Google Scholar 

  • Reinhard J, Trauzettel-Klosinski S (2003) Nasotemporal overlap of retinal ganglion cells in humans: a functional study. Invest Ophthalmol Vis Sci 44: 1568–1572

    Article  PubMed  Google Scholar 

  • Robb RM (1985) Regional changes in retinal pigment epithelial cell density during ocular development. Invest Ophthalmol Vis Sci 26: 614–620

    PubMed  CAS  Google Scholar 

  • Robinson SR, Hendrickson A (1995) Shifting relationships between photoreceptors and pigment epithelial cells in monkey retina: implications for the development of retinal topography. Vis Neurosci 12: 767–778

    PubMed  CAS  Google Scholar 

  • Röhrenbeck J, Wässle H, Boycott BB (1989) Horizontal cells in the monkey retina: immunocytochemical staining with antibodies against calcium binding proteins. Eur J Neurosci 1: 407–420

    PubMed  Google Scholar 

  • Roorda A, Williams DR (1999) The arrangement of the three cone classes in the living human eye. Nature 397: 520–522

    Article  PubMed  CAS  Google Scholar 

  • Roorda A, Metha AB, Lennie P, Williams DR (2001) Packing arrangement of the three cone classes in primate retina. Vis Res 41: 1291–1306

    PubMed  CAS  Google Scholar 

  • Sandercoe TM, Madigan MC, Billson FA, Penfold PL, Provis JM (1999) Astrocyte proliferation during development of the human retinal vasculature. Exp Eye Res 69: 511–523

    Article  PubMed  CAS  Google Scholar 

  • Schein SJ (1988) Anatomy of macaque fovea and spatial densities of neurons in foveal representation. J Comp Neurol 269: 479–505

    Article  PubMed  CAS  Google Scholar 

  • Sharpe LT, Stockman A, Jägle H, Nathans J (1999) Opsin genes, cone photopigments, color vision and color blindness. In: KR Gegenfurtner, Sharpe LT (eds) Color vision — from genes to perception. Cambridge University Press, Cambridge, UK, pp 3–51

    Google Scholar 

  • Silveira LCL, Yamada ES, Perry VH, Picanco-Diniz CW (1994) M and P retinal ganglion cells of diurnal and nocturnal New World monkeys. Neuroreport 5: 2077–2081

    PubMed  CAS  Google Scholar 

  • Silveira LCL, Lee BB, Yamada ES, Kremers J, Hunt DM (1998) Postreceptoral mechanisms of colour vision in new world primates. Vis Res 38: 3329–3337

    PubMed  CAS  Google Scholar 

  • Snodderly DM, Weinhaus RS (1990) Retinal vasculature of the fovea of the squirrel monkey Saimiri sciureus: three-dimensional architecture, visual screening and relationships to the neuronal layers. J Comp Neurol 297: 145–163

    PubMed  CAS  Google Scholar 

  • Snodderly DM, Weinhaus RS, Choi JC (1992) Neuralvascular relationships in central retina of macaque monkeys (Macaca fascicularis). J Neurosci 12: 1169–1193

    PubMed  CAS  Google Scholar 

  • Snodderly DM, Sandstrom MM, Leung IY-F, Zucker CL, Neuringer M (2002) Retinal pigment epithelial cell distribution in central retina of rhesus monkeys. Invest Ophthalmol Vis Sci 43: 2815–2818

    PubMed  Google Scholar 

  • Spedick MJ, Beauchamp GR (1986) Retinal vascular and optic nerve abnormalities in albinism. J Pediatr Ophthalmol Strabismus 23: 58–63

    PubMed  CAS  Google Scholar 

  • Springer AD (1999) New role for the primate fovea: a retinal excavation determines photoreceptor deployment and shape. Vis Neurosci 16: 629–636.

    Article  PubMed  CAS  Google Scholar 

  • Springer A, Hendrickson A (2004) Development of the primate fovea. 1. Use of finite element analysis models to identify mechanical variables affecting pit formation. Vis Neurosci 21: 53–62

    PubMed  CAS  Google Scholar 

  • Stone J, Leicester J, Sherman M (1973) The naso-temporal division of the monkey’s retina. J Comp Neurol 150: 333–348

    Article  PubMed  CAS  Google Scholar 

  • Streeten BW (1969) Development of the human retinal pigment epithelium and the posterior segment. Arch Ophthalmol 81: 383–394

    PubMed  CAS  Google Scholar 

  • Swain PK, Hicks D, Mears AJ, Apel IJ, Smith JE, John SK, Hendrickson AE, Milam AH, Swaroop A (2001) Multiple phosphorylated isoforms of NRL are specifically expressed in photoreceptors. J Biol Chem 276: 36824–36830

    PubMed  CAS  Google Scholar 

  • Szél A, Diamanstein T, Röhlich P (1988) Identification of the blue sensitive cones in the mammalian retina by anti-visual pigment antibody. J Comp Neurol 273: 593–602

    PubMed  Google Scholar 

  • Thompson DA, Gal A (2003) Vitamin A metabolism in the retinal pigment epithelium: genes, mutations and diseases. Prog Retin Eye Res 22: 683–703

    Article  PubMed  CAS  Google Scholar 

  • Tootell RBH, Switkes E, Silverman MS, Hamilton SL (1988) Functional anatomy of macaque striate cortex. II. Retinotopic organization. J Neurosci 8: 1531–1568

    PubMed  CAS  Google Scholar 

  • Troilo D, Howland HC, Judge SJ (1993) Visual optics and retinal cone topography in the common marmoset (Callithrix jacchus). Vis Res 33: 1301–1310

    PubMed  CAS  Google Scholar 

  • Wässle H, Boycott BB (1991) Functional architecture of the mammalian retina. Physiol Rev 71: 447–480

    PubMed  Google Scholar 

  • Wässle H, Grünert U, Röhrenbeck J, Boycott BB (1990) Retinal ganglion cell density and cortical magnification factor in the primate. Vis Res 30: 1897–1911

    PubMed  Google Scholar 

  • Weinhaus RS, Burke JM, Delori FC, Snodderly DM (1995) Comparison of fluorescein angiography with microvascular anatomy of macaque retinas. Exp Eye Res 61: 1–16

    Article  PubMed  CAS  Google Scholar 

  • Wikler KC, Rakic P (1990) Distribution of photoreceptor subtypes in the retina of diurnal and nocturnal primates. J Neurosci 10: 3390–3401

    PubMed  CAS  Google Scholar 

  • Wilder HC, Grünert U, Lee BB, Martin PR (1996) Topography of ganglion cells and photoreceptors in the retina of a New World monkey: the marmoset Callithrix jacchus. Vis Neurosci 13: 335–352

    Article  PubMed  CAS  Google Scholar 

  • Wolin LR, Massopust LC Jr (1967) Characteristics of the ocular fundus of the primate. J Anat 101: 693–699

    PubMed  CAS  Google Scholar 

  • Xiao M, Hendrickson A (2000) Spatial and temporal expression of short, long/medium or both opsins in human fetal cones. J Comp Neurol 425: 545–559

    Article  PubMed  CAS  Google Scholar 

  • Yamada E (1969) Some structural features of the fovea centralis in the human retina. Arch Ophthalmol 82: 151–155

    PubMed  CAS  Google Scholar 

  • Yuodelis C, Hendrickson A (1986) A qualitative and quantitative analysis of the human fovea during development. Vis Res 26: 847–855

    PubMed  CAS  Google Scholar 

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    Jan M. Provis

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Hendrickson, A. (2005). Organization of the Adult Primate Fovea. In: Penfold, P.L., Provis, J.M. (eds) Macular Degeneration. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26977-0_1

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