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Radionuclide Therapy for Skin Malignancies

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Therapeutic Nuclear Medicine

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Skin cancer is the most common human malignancy. Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) constitute approximately over 95 % (80 and 16 %, respectively) of new cases of non-melanoma skin cancers. It is estimated that over 1.3 million non-melanoma skin cancers will develop annually in the United States (Neville et al. 2007). Moreover, there are many conditions, especially actinic keratosis (AK) and Bowen’s disease, which can progress to invasive SCC. Treatment methods depend on the various clinical indications and histopathology of the malignancy. The three major therapeutic methods are topical application of chemotherapeutic agents, radiotherapy, and surgical management (Bolognia et al. 2003; Fitzpatrick et al. 2008). In this chapter, conventional therapeutic modalities for skin cancer managements will be briefly discussed and a new treatment modality using various beta-emitting radionuclides will be introduced.

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Authors and Affiliations

  1. Department of Nuclear Medicine, Yonsei University College of Medicine, 250 Seongsan-ro, Seodaemun-gu, Seoul, 120-752, Korea

    Arthur Eung-Hyuk Cho & Jong Doo Lee

  2. Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea

    Min-Geol Lee

Authors
  1. Arthur Eung-Hyuk Cho
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  2. Min-Geol Lee
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  3. Jong Doo Lee
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Correspondence to Jong Doo Lee .

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Editors and Affiliations

  1. THERANOSTICS Center for Molecular, Radiotherapy and Molecular Imaging, ENETS Center of Excellence, Bad Berka, Germany

    Richard P. Baum

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© 2012 Springer-Verlag Berlin Heidelberg

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Cho, A.EH., Lee, MG., Lee, J.D. (2012). Radionuclide Therapy for Skin Malignancies. In: Baum, R. (eds) Therapeutic Nuclear Medicine. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_712

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  • DOI: https://doi.org/10.1007/174_2012_712

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  • Print ISBN: 978-3-540-36718-5

  • Online ISBN: 978-3-540-36719-2

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