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Immunosuppression and Kidney Transplantation

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Pharmacology of Immunosuppression

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 272))

Abstract

Immunosuppression is complex, fraught with on-target and off-target adverse effects, and hard to get right but is the key to successful allotransplantation. Herein, we review the key immunosuppressive agent classes used for kidney transplant, highlighting mechanisms of action and typical clinical use.

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Authors and Affiliations

  1. Division of Nephrology, University of Virginia School of Medicine, Charlottesville, VA, USA

    Jeanne Kamal & Alden Doyle

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  1. Jeanne Kamal
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  2. Alden Doyle
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Corresponding author

Correspondence to Alden Doyle .

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Editors and Affiliations

  1. Heart and Vascular Institute, Pennsylvania State University, Hershey, PA, USA

    Howard J. Eisen

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Kamal, J., Doyle, A. (2021). Immunosuppression and Kidney Transplantation. In: Eisen, H.J. (eds) Pharmacology of Immunosuppression. Handbook of Experimental Pharmacology, vol 272. Springer, Cham. https://doi.org/10.1007/164_2021_546

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