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Risk Factors for Lower Extremity Amputation in Patients with Diabetic Foot Ulcer

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Pressure Injury, Diabetes and Negative Pressure Wound Therapy

Part of the book series: Recent Clinical Techniques, Results, and Research in Wounds ((RCTRRW,volume 3))

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Abstract

Multiple factors get involved with the pathophysiology and affect the severity of diabetic foot ulcers (DFUs) leading to lower extremity amputation (LEA). LEA in diabetic patients is not a spontaneous occurrence; nevertheless, there is pathway into it. Both metabolic and non-metabolic risk factors are cross-linked associated with DFU leading to amputation pathway. Therefore, it is important to identify all these potential risk factors: which factors can be modified and which factors cannot be modified at all. Critical risk factors may include disease-specific factors, or patient’s general characteristics, but also, in a broader context, extrinsic factors such as healthcare system and socioeconomic and environmental factors contribute to the overall risk in the distant past. These will be discussed in more detail later in the chapter.

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Authors and Affiliations

  1. Division of Endocrinology, Department of Internal Medicine, Medical Faculty of Diponegoro University, Dr. Kariadi General Hospital, Semarang, Indonesia

    Tjokorda Gde Dalem Pemayun M.D., Ph.D.

  2. Department of Internal Medicine, A. M. Parikesit General Hospital, Kutai Kartanegara, Indonesia

    Ridho M. Naibaho M.D.

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  1. Tjokorda Gde Dalem Pemayun M.D., Ph.D.
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Correspondence to Tjokorda Gde Dalem Pemayun M.D., Ph.D. .

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    Melvin A. Shiffman

  2. Newport Beach, CA, USA

    Mervin Low

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Pemayun, T.G.D., Naibaho, R.M. (2017). Risk Factors for Lower Extremity Amputation in Patients with Diabetic Foot Ulcer. In: Shiffman, M., Low, M. (eds) Pressure Injury, Diabetes and Negative Pressure Wound Therapy. Recent Clinical Techniques, Results, and Research in Wounds, vol 3. Springer, Cham. https://doi.org/10.1007/15695_2017_47

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