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Chitosan-Based Biosensor Fabrication and Biosensing Applications

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Book cover Chitosan for Biomaterials III

Part of the book series: Advances in Polymer Science ((POLYMER,volume 287))

Abstract

Recent years have seen tremendous interest among researchers in the field of biosensors for the application of medical and agricultural products, processed food, and environmental monitoring. To prepare a stable and reliable biosensor, immobilization of biological responses elements (BRE) plays a critical role. Chitosan, a natural polysaccharide with non-toxic and gellable properties, and the presence of functional groups would act as a suitable substrate material. The presence of functional groups would provide cross-linking moieties increasing the mechanical stability, immobilization of BRE and nanomaterials. Additionally, a chitosan composite/nanocomposite-based biosensor would provide enhanced conductivity and sensitivity of detecting various biological analytes such as glucose, H2O2, antigens, DNA, and biomolecules. This review provides a comprehensive understanding of various strategies of utilizing chitosan as a substrate for various biosensing applications.

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Authors and Affiliations

  1. Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, India

    Sivashanmugam Amirthalingam & Jayakumar Rangasamy

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  1. Sivashanmugam Amirthalingam
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  2. Jayakumar Rangasamy
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Correspondence to Jayakumar Rangasamy .

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  1. Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham (University), Kochi, India

    R. Jayakumar

  2. Department of Chemistry, Hindustan Institute of Technology and Science, Padur, Chennai, India

    M. Prabaharan

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Amirthalingam, S., Rangasamy, J. (2021). Chitosan-Based Biosensor Fabrication and Biosensing Applications. In: Jayakumar, R., Prabaharan, M. (eds) Chitosan for Biomaterials III. Advances in Polymer Science, vol 287. Springer, Cham. https://doi.org/10.1007/12_2021_85

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