¹H CRAMPS NMR of Polypeptides in the Solid State

The research of the solid high-resolution NMR rapidly developed recently, and the cross-polarization-magicangle spinning (CP-MAS) method is most commonly used for the ¹³C and ¹⁵N NMR measurements of organic compounds in the solid state. Very recently, the solid high-resolution proton NMR research developed [1–7] because both quality and quantities are high for the potential of information of the hydrogen nucleus. Study example of solid secondary structure (main-chain conformation) of polypeptide is introduced on the basis of the proton chemical shift this-focus. Therefore, the author introduces the research result of recent proton combined rotation and multiple pulse spectroscopy (CRAMPS) NMR of polypeptides in this chapter. In the attractiveness, the proton CRAMPS NMR research has just begun yet, and it has a further unprecedented possibility of developing in future. This review is the happiness, if it is useful for the future of your scientific research.