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Determination of Acrylamide in Various Food Matrices

Evaluation of LC and GC mass spectrometric methods

  • Conference paper
Chemistry and Safety of Acrylamide in Food

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 561))

Abstract

Recent concerns surrounding the presence of acrylamide in many types of thermally processed food have brought about the need for the development of analytical methods suitable for determination of acrylamide in diverse matrices with the goals of improving overall confidence in analytical results and better understanding of method capabilities. Consequently, the results are presented of acrylamide testing in commercially available food products — potato fries, potato chips, crispbread, instant coffee, coffee beans, cocoa, chocolate and peanut butter, obtained by using the same sample extract. The results obtained by using LC-MS/MS, GC/MS (EI), GC/HRMS (EI) — with or without derivatization — and the use of different analytical columns, are discussed and compared with respect to matrix borne interferences, detection limits and method complexities.

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References

  • Ahn J.S., Castle L., Clarke D.B., Lloyd A.S., Philo M.R., and Speck D.R., 2002, Verification of the findings of acrylamide in heated foods, Food Addit. Contam. 19:1116–1124.

    Article  CAS  Google Scholar 

  • Andrawes, F., Greenhouse, S., and Draney, D., 1987, Chemistry of acrylamide bromination for trace analysis by gas chromatography and gas chromatography-mass spectrometry, J. Chrom. 399:269–275.

    Article  CAS  Google Scholar 

  • Becalski, A., Lau, B.P-Y., Lewis, D., and Seaman, S., 2003, Acrylamide in foods: occurrence, sources and modeling, J. Agric. Food Chem. 51:802–808.

    Article  CAS  Google Scholar 

  • Biedermann, M., Biedermann-Brem, S., Noti, A., Grob, K., Egli, P., and Maendli, H., 2002, Two GC-MS methods for the analysis of acrylamide in foods, Mitt. Lebensm. Hyg. 93:638–652.

    CAS  Google Scholar 

  • Cavalli, S., Maurer R., and Hoefler F., 2003, Fast determination of acrylamide in food samples using accelerated solvent extraction followed by ion chromatography with UV or MS detection, LC-GC, application notebook 35.

    Google Scholar 

  • Castle, L., Campos, M.-J, and Gilbert, J., 1991, Determination of acrylamide monomer in hydroponically grown tomato fruits by capillary gas chromatography-mass spectrometry, J. Sci. Food Agric. 54:549–555.

    CAS  Google Scholar 

  • Castle, L., 1993, Determination of acrylamide monomer in mushrooms grown on the polyacrylamide gel, J. Agric. Food Chem. 41:1261–1263.

    Article  CAS  Google Scholar 

  • Clarke, D. B., Kelly, J., and Wilson, L. A., 2002, Assessment of Performance of Laboratories in Determining Acrylamide in Crispbread, J. AOAC Int. 85:1370–1373.

    CAS  Google Scholar 

  • Fauhl, C., Klaffke, H., Mathar, W., Palavinskas, R., and Wittkowski, R., 2002, Acrylamide Interlaboratory Study (February 10, 2002); http://www.bgvv.de/cm/245/proficiency_testing_studie.pdf

    Google Scholar 

  • Gertz, C., and Klostermann, S., 2002, Analysis of acrylamide and mechanisms of its formation in deep-fried products, Eur. J. Lipid Sci. Technol. 104:762–771.

    Article  CAS  Google Scholar 

  • Haase N.U., Matthaus B., and Vosmann K., 2003, Acrylamide formation in foodstuffs — Minimising strategies for potato crisps, Deutsche Lebensmittel-Rundschau 99:87–90.

    CAS  Google Scholar 

  • International Agency for Research on Cancer, Lyon, 1994, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, 60:389–433.

    Google Scholar 

  • La Calle, Beatriz de; Ostermann, Ole; Wenzl, Thomas; Anklam, Elke, 2004, Report European Workshop on Analytical Methods for the Determination of Acrylamide in Food Products (June, 2004); http://www.irmm.jrc.be/ffu/acrylamide.html

    Google Scholar 

  • Nemoto, S., Takatsuki, S., Sasaki, K., and Maitani, T., 2002, Determination of acrylamide in foods by GC/MS using 13C-labeled acrylamide as an internal standard, J. Food Hyg. Soc. Jap. 43:371–376.

    Article  CAS  Google Scholar 

  • Ono, H., Chuda, Y., Ohnishi-Kameyama, M., Yada, H., Ishizaka, M., Kobayashi, H., and Yoshida, M., 2003, Analysis of acrylamide by LC-MS/MS and GC-MS in processed Japanese foods, Food Addit. Contam 20:215–220.

    Article  CAS  Google Scholar 

  • Rosen, J., and Hellenas, K-E., 2002, Analysis of acrylamide in cooked foods by liquid chromatography tandem mass spectrometry, Analyst 127:880–882.

    Article  CAS  Google Scholar 

  • Rothweiler B., and Prest, H., 2003, Rapid screening for acrylamide in foods using GC-MS with positive chemical ionization, LC-GC, application notebook 34.

    Google Scholar 

  • Sanders, R. A., Zyzak, D. V., Stojanovic, M., Tallmadge, D. H., Eberhart, B. L., and Ewald, D. K., 2002, An LC/MS acrylamide method and its use in investigating the role of asparagine, Acrylamide Symposium, 116th Annual AOAC International Meeting, Los Angeles, September 26, 2002.

    Google Scholar 

  • Swiss Federal Office of Public Health, 2002, Determination of acrylamide in food, (August 10, 2002); http://www.bag.admin.ch/verbrau/aktuell/d/AA_methode.pdf

    Google Scholar 

  • Takatsuki, S., Nemoto, S., Sasaki, K., and Maitani, T., 2003, Determination of acrylamide in processed foods by LC/MS using column switching, J. Food Hyg. Soc. Jap. 44:89–95.

    Article  CAS  Google Scholar 

  • Tareke, E., Rydberg, P., Karlsson, P., Eriksson, S., and Tornqvist, M., 2000, Acrylamide: a cooking carcinogen? Chem. Res. Toxicol. 13:517–522.

    Article  CAS  Google Scholar 

  • Tareke, E., Rydberg, P., Karlsson, P., Eriksson, S., and Tornqvist, M., 2002, Analysis of acrylamide, a carcinogen formed in heated foodstuffs, J. Agric. Food Chem. 50:4998–5006.

    Article  CAS  Google Scholar 

  • Tateo, F., and Bononi, M., 2003, Ital. J. Food Sci. 15:149–151.

    CAS  Google Scholar 

  • US FDA, 2003, Detection and quantitation of acrylamide in foods (February 24, 2003); http://www.cfsan.fda.gov/∼dms/acrylami.html.

    Google Scholar 

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Becalski, A., Lau, B.P.Y., Lewis, D., Seaman, S.W., Sun, W.F. (2005). Determination of Acrylamide in Various Food Matrices. In: Friedman, M., Mottram, D. (eds) Chemistry and Safety of Acrylamide in Food. Advances in Experimental Medicine and Biology, vol 561. Springer, Boston, MA. https://doi.org/10.1007/0-387-24980-X_20

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