Skip to main content
SpringerLink
Log in

Synthesis and comparative study on the antimicrobial activity of hybrid materials based on silver nanoparticles (AgNps) stabilized by polyvinylpyrrolidone (PVP)

  • Original Article
  • Published:
Journal of Chemical Biology

Abstract

Hybrid materials based on polyvinylpyrrolidone (PVP) with silver nanoparticles (AgNps) were synthesized applying two different strategies based on thermal or chemical reduction of silver ions to silver nanoparticles using PVP as a stabilizer. The formation of spherical silver nanoparticles with diameter ranging from 9 to 16 nm was confirmed by TEM analysis. UV-vis and FTIR spectroscopy were also applied to confirm the successful formation of AgNps. The antibacterial activity of the synthesized AgNPs/PVP against etalon strains of three different groups of bacteria—Staphylococcus aureus (S. aureus; gram-positive bacteria), Escherichia coli (E. coli; gram-negative bacteria), Pseudomonas aeruginosa (P. aeruginosa; non-ferment gram-negative bacteria), as well as against spores of Bacillus subtilis (B. subtilis) was studied. AgNps/PVP were tested for the presence of fungicidal activity against different yeasts and mold such as Candida albicans, Candida krusei, Candida tropicalis, Candida glabrata, and Aspergillus brasiliensis. The hybrid materials showed a strong antimicrobial effect against the tested bacterial and fungal strains and therefore have potential applications in biotechnology and biomedical science.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Scheme 1
Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Sharma VK, Yngard RA, Lin Y (2009) Adv Colloid Interface Sci 145:83–96

    Article  CAS  Google Scholar 

  2. Sondi I, Salopek-Sondi B (2004) J Colloid Interface Sci 275:177–182

    Article  CAS  Google Scholar 

  3. Rai M, Yadav A, Gade A (2009) Biotechnol Adv 27:76–83

    Article  CAS  Google Scholar 

  4. Ray S, Mohan R, Singh JK, Samantaray MK, Shaikh MM, Panda D, Ghosh P (2007) J Am Chem Soc 129:15042–15053

    Article  CAS  Google Scholar 

  5. Lee HY, Park HK, Lee YM, Kim K, Park SB (2007) Chem Commun 28:2959–2961

    Article  Google Scholar 

  6. Zhang Y, Peng H, Huang W, Zhou Y, Yan D (2008) J Colloid Interface Sci 325:371–376

    Article  CAS  Google Scholar 

  7. Panacek A, Kvitek L, Prucek R, Kolar M, Vecerova R, Pizurova N, Sharma VK, Nevecna T, Zboril R (2006) J Phys Chem B 110:16248–16253

    Article  CAS  Google Scholar 

  8. Pal S, Song JM (2007) Appl Environ Microbiol 73:1712–1720

    Article  CAS  Google Scholar 

  9. Kvitek L, Panacek A, Soukupova J, Kolar M, Vecerova R, Prusek R, Holecova M, Zboril R (2008) J Phys Chem C 112:5825

    Article  CAS  Google Scholar 

  10. Wang H, Qiao X, Chen J, Ding Sh (2005) Colloid Surfaces Physicochem Eng Aspect 256:111–115

    Article  CAS  Google Scholar 

  11. Zielinska A, Skwarek E, Zaleska A, Gazda M, Hupka J (2009) Procedia Chem 1:1560–1566

    Article  CAS  Google Scholar 

  12. Huang HH, Ni XP, Loy GL, Chew CH, Tan KL, Loh FC, Deng JF, Xu GQ (1996) Langmuir 12:909–912

    Article  CAS  Google Scholar 

  13. Carotenuto G (2001) Appl Organomet Chem 15:344

    Article  CAS  Google Scholar 

  14. Sheikh N, Akhavan A, Kassaee MZ (2009) Physica E 42:132–135

    Article  CAS  Google Scholar 

  15. Li T, Park HG, Choi S-H (2007) Mater Chem Phys 105:325–330

    Article  CAS  Google Scholar 

  16. Shin HS, Yang HJ, Kim SB, Lee MS (2004) J Colloid Interface Sci 274:89–94

    Article  CAS  Google Scholar 

  17. Tsuji T, Thang D-H, Okazaki Y, Nakanishi M, Tsuboi Y, Tsuji M (2008) Appl Surf Sci 254:5224–5230

    Article  CAS  Google Scholar 

  18. Cho K-H, Park J-E, Osaka T, Park S-G (2005) Elecrochim Acta 51:956–960

    Article  CAS  Google Scholar 

  19. Falletta E, Bonini M, Fratini E, Lo Nostro A, Pesavento G, Becheri A et al (2008) J Phys Chem 112:11758–11766

    CAS  Google Scholar 

  20. Roe D, Karandikar B, Bonn-Savage N, Gibbins B, Roullet JB (2008) J Antimicrob Chemother 61:869–876

    Article  CAS  Google Scholar 

  21. Zeng F, Hou C, Wu SZ, Liu XX, Tong Z, Yu SN (2007) Nanotechnology 18:1–8

    Google Scholar 

  22. Bryaskova R, Pencheva D, Kale GM, Lad U, Kantardjiev T (2010) J Colloid Interface Sci 349:77–85

    Article  CAS  Google Scholar 

  23. Pencheva D, Bryaskova R, Kantardjiev T (2010) Clin Microbiol Infect 16(suppl2):S670

    Google Scholar 

  24. CLSI/NCCLS M26-A - Methods for determining bactericidal activity of antimicrobial agents; Approved Guideline, September (1999).

  25. CLSI/NCCLS M27- A2 - Reference method for broth dilution antifungal susceptibility testing of yeasts; Approved Standard—Second Edition

  26. Wiley B, Sun Y, Mayers B, Xia Y (2005) Chem Eur J 11:454–463

    Article  CAS  Google Scholar 

  27. Pal S, Tak YK, Song JM (2007) Appl Environ Microbiol 27:1712–1720

    Article  Google Scholar 

  28. Bryaskova R, Pencheva D, Kyulavska M, Bozukova D, Debuigne A, Detrembleur C (2010) J Colloid Interface Sci 344:424–428

    Article  CAS  Google Scholar 

  29. Panacek A, Kolar M, Vecerova R, Prucek R, Soukupova J, Krystof V, Hamal P, Zboril R, Kvitek L (2009) Biomaterials 30:6333–6340

    Article  CAS  Google Scholar 

Download references

Acknowledgments

This work was funded and supported by project no. 10772 of the University of Chemical Technology and Metallurgy Science Fund “Research Investigations”.

Author information

Authors and Affiliations

  1. Department of Polymer Engineering, University of Chemical Technology and Metallurgy, 8 Kl.Ohridski, 1756, Sofia, Bulgaria

    Rayna Bryaskova & Stanislav Nikolov

  2. Bul Bio-National Centre of Infectious and Parasitic Diseases, 26 Yanko Sakazov, 1504, Sofia, Bulgaria

    Daniela Pencheva

  3. National Centre of Infectious and Parasitic Diseases, 26 Yanko Sakazov, 1504, Sofia, Bulgaria

    Todor Kantardjiev

Authors
  1. Rayna Bryaskova
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Daniela Pencheva
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Stanislav Nikolov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Todor Kantardjiev
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rayna Bryaskova.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bryaskova, R., Pencheva, D., Nikolov, S. et al. Synthesis and comparative study on the antimicrobial activity of hybrid materials based on silver nanoparticles (AgNps) stabilized by polyvinylpyrrolidone (PVP). J Chem Biol 4, 185–191 (2011). https://doi.org/10.1007/s12154-011-0063-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12154-011-0063-9

Keywords

Search

Navigation