References
Barr, F.A. (2013). Review series: Rab GTPases and membrane identity: causal or inconsequential? J Cell Biol 202, 191–199.
Edwards, S.L., Charlie, N.K., Richmond, J.E., Hegermann, J., Eimer, S., and Miller, K.G. (2009). Impaired dense core vesicle maturation in Caenorhabditis elegans mutants lacking Rab2. J Cell Biol 186, 881–895.
Hannemann, M., Sasidharan, N., Hegermann, J., Kutscher, L.M., Koenig, S., and Eimer, S. (2012). TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans. PLoS Genet 8, e1002722.
Huyghe, J.R., Jackson, A.U., Fogarty, M.P., Buchkovich, M.L., Stančáková, A., Stringham, H.M., Sim, X., Yang, L., Fuchsberger, C., Cederberg, H., Chines, P.S., Teslovich, T.M., Romm, J.M., Ling, H., McMullen, I., Ingersoll, R., Pugh, E.W., Doheny, K.F., Neale, B.M., Daly, M.J., Kuusisto, J., Scott, L.J., Kang, H.M., Collins, F.S., Abecasis, G.R., Watanabe, R.M., Boehnke, M., Laakso, M., Mohlke, K.L. (2013). Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat Genet 45, 197–201.
Kim, T., Gondre-Lewis, M.C., Arnaoutova, I., and Loh, Y.P. (2006). Densecore secretory granule biogenesis. Physiology (Bethesda) 21, 124–133.
Strawbridge, R.J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J.R., Travers, M.E., Bouatia-Naji, N., Dimas, A.S., Nica, A., Wheeler, E., Chen, H., Voight, B.F., Taneera, J., Kanoni, S., Peden, J.F., Turrini, F., Gustafsson, S., Zabena, C., Almgren, P., Barker, D.J.P., Barnes, D., Dennison, E.M., Eriksson, J.G., Eriksson, P., Eury, E., Folkersen, L., Fox, C.S., Frayling, T.M., Goel, A., Gu, H.F., Horikoshi, M., Isomaa, B., Jackson, A.U., Jameson, K.A., Kajantie, E., Kerr-Conte, J., Kuulasmaa, T., Kuusisto, J., Loos, R.J.F., Luan, J., Makrilakis, K., Manning, A.K., Martínez-Larrad, M.T., Narisu, N., Nastase Mannila, M., Ohrvik, J., Osmond, C., Pascoe, L., Payne, F., Sayer, A.A., Sennblad, B., Silveira, A., Stancáková, A., Stirrups, K., Swift, A. J., Syvänen, A.C., Tuomi, T., van ’t Hooft, F.M., Walker, M., Weedon, M.N., Xie, W., Zethelius, B., Zethelius, B., Zethelius, B., Zethelius, B., Zethelius, B., Zethelius, B., Ongen, H., Mälarstig, A., Hopewell, J.C., Saleheen, D., Chambers, J., Parish, S., Danesh, J., Kooner, J., Ostenson, C.G., Lind, L., Cooper, C.C., Serrano-Ríos, M., Ferrannini, E., Forsen, T.J., Clarke, R., Franzosi, M.G., Seedorf, U., Watkins, H., Froguel, P., Johnson, P., Deloukas, P., Collins, F.S., Laakso, M., Dermitzakis, E.T., Boehnke, M., McCarthy, M.I., Wareham, N.J., Groop, L., Pattou, F., Gloyn, A.L., Dedoussis, G.V., Lyssenko, V., Meigs, J.B., Barroso, I., Watanabe, R.M., Ingelsson, E., Langenberg, C., Hamsten, A., Florez, J. C. (2011). Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes 60, 2624–2634.
Sumakovic, M., Hegermann, J., Luo, L., Husson, S.J., Schwarze, K., Olendrowitz, C., Schoofs, L., Richmond, J., and Eimer, S. (2009). UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. J Cell Biol 186, 897–914.
Zhang, Z., and Liu, Z. (2016). Paneth cells: the hub for sensing and regulating intestinal flora. Sci China Life Sci 59, 463–467.
Acknowledgements
This work was supported by the National Natural Science Foundation of China (81570504, 31471337).
Author information
Authors and Affiliations
Corresponding authors
Electronic supplementary material
Rights and permissions
About this article
Cite this article
Jiang, P., Pan, Y., Liu, Z. et al. SGSM2, a putative Rab2a GAP, regulates lysozyme sorting in Paneth cells. Sci. China Life Sci. 61, 860–863 (2018). https://doi.org/10.1007/s11427-017-9267-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11427-017-9267-9