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Effects of guided imagery on biobehavioral factors in women with fibromyalgia

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Abstract

Women diagnosed with fibromyalgia (N = 72) participated in a 10-week randomized trial to examine the effectiveness of guided imagery on self-efficacy, perceived stress, and selected biobehavioral factors (FMS symptoms; immune biomarkers). Participants in both guided imagery and usual care control conditions completed measures and donated 3 cc of blood at baseline, 6- and 10-weeks. A mixed effects linear model to test for differences between groups for all behavioral and biologic variables demonstrated that after 10 weeks of daily intervention use, guided imagery participants reported statistically significant increases in self-efficacy and statistically significant decreases in stress, fatigue, pain, and depression. There were no statistically significant changes in biomarker levels, although total group C-reactive protein was elevated at baseline (4.7 mg/L), indicating an inflammatory process. Subsequent studies should be undertaken to more fully elucidate the biobehavioral aspects of nonpharmacological intervention effectiveness.

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Acknowledgments

Supported by the National Institute of Nursing Research through Grant #P30 NR011403 M. J. Grap (PI). This work was supported, in part, by award number UL1RR031990 from the National Center for Research Resources and NIH Roadmap for Medical Research, National Institutes of Health.

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Correspondence to Victoria Menzies.

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Menzies, V., Lyon, D.E., Elswick, R.K. et al. Effects of guided imagery on biobehavioral factors in women with fibromyalgia. J Behav Med 37, 70–80 (2014). https://doi.org/10.1007/s10865-012-9464-7

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