Skip to main content

Advertisement

Log in

Late-onset bleb-related endophthalmitis caused by Streptococcus pseudopneumoniae

  • Case Report
  • Published:
International Ophthalmology Aims and scope Submit manuscript

Abstract

We report our findings in a 63-year-old male who developed late-onset bleb-related endophthalmitis. The patient had undergone glaucoma surgery 46 years earlier, and had a thin-walled cystic bleb prior to the endophthalmitis in his right eye. He underwent immediate vitrectomy with intravitreal injections of ceftazidime and vancomycin. After surgery, he was given topical 0.5 % moxifloxacin and 1 % vancomycin, intravenous doripenem, and oral minocycline. Culture of the vitreous specimen identified Streptococcus pseudopneumoniae by 16S rRNA sequence analysis, by optochin susceptibility test, and by bile solubility test. Our findings indicate that S. pseudopneumoniae can be isolated from a late-onset bleb-related endophthalmitis and that molecular analysis and phenotypic testing can be accurate methods to identify S. pseudopneumoniae.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Mandelbaum S, Forster RK, Gelender H, Culbertson W (1985) Late onset endophthalmitis associated with filtering blebs. Ophthalmology 92:964–972

    Article  CAS  PubMed  Google Scholar 

  2. Leng T, Miller D, Flynn HW Jr, Jacobs DJ, Gedde SJ (2011) Delayed-onset bleb-associated endophthalmitis (1996–2008): causative organisms and visual acuity outcomes. Retina 31:344–352

    Article  PubMed  Google Scholar 

  3. Miller JJ, Scott IU, Flynn HW Jr, Smiddy WE, Corey RP, Miller D (2004) Endophthalmitis caused by Streptococcus pneumoniae. Am J Ophthalmol 138:231–236

    Article  PubMed  Google Scholar 

  4. Sistek V, Boissinot M, Boudreau DK, Huletsky A, Picard FJ, Bergeron MG (2012) Development of a real-time PCR assay for the specific detection and identification of Streptococcus pseudopneumoniae using the recA gene. Clin Microbiol Infect 18:1089–1096

    Article  CAS  PubMed  Google Scholar 

  5. Arbique JC, Poyart C, Trieu-Cuot P, Quesne G, Carvalho Mda G, Steigerwalt AG, Morey RE, Jackson D, Davidson RJ, Facklam RR (2004) Accuracy of phenotypic and genotypic testing for identification of Streptococcus pneumoniae and description of Streptococcus pseudopneumoniae sp. nov. J Clin Microbiol 42:4686–4696

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  6. Harf-Monteil C, Granello C, Le Brun C, Monteil H, Riegel P (2006) Incidence and pathogenic effect of Streptococcus pseudopneumoniae. J Clin Microbiol 44:2240–2241

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  7. Keith ER, Podmore RG, Anderson TP, Murdoch DR (2006) Characteristics of Streptococcus pseudopneumoniae isolated from purulent sputum samples. J Clin Microbiol 44:923–927

    Article  PubMed Central  PubMed  Google Scholar 

  8. Laurens C, Michon AL, Marchandin H, Bayette J, Didelot MN, Jean-Pierre H (2012) Clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates in France. Antimicrob Agents Chemother 56:4504–4507

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  9. Ikryannikova LN, Lapin KN, Malakhova MV, Filimonova AV, Ilina EN, Dubovickaya VA, Sidorenko SV, Govorun VM (2011) Misidentification of alpha-hemolytic streptococci by routine tests in clinical practice. Infect Genet Evol 11:1709–1715

    Article  CAS  PubMed  Google Scholar 

  10. Traub WH, Leonhard B (1997) Comparative susceptibility of clinical group A, B, C, F, and G beta-hemolytic streptococcal isolates to 24 antimicrobial drugs. Chemotherapy 43:10–20

    Article  CAS  PubMed  Google Scholar 

  11. Tuohy M, Washington JA (1997) Antimicrobial susceptibility of viridans group streptococci. Diagn Microbiol Infect Dis 29:277–280

    Article  CAS  PubMed  Google Scholar 

  12. Mochizuki K, Kumada M, Suemori S, Kawakami H, Sawada A, Yamamoto T, Mikamo H (2009) Streptococcus intermedius-associated late-onset endophthalmitis after trabeculectomy with adjunctive mitomycin C. J Glaucoma 18:79–80

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The authors have no proprietary or financial interests in any products used in this study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hideaki Kawakami.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kawakami, H., Nakane, Y., Inuzuka, H. et al. Late-onset bleb-related endophthalmitis caused by Streptococcus pseudopneumoniae . Int Ophthalmol 34, 643–646 (2014). https://doi.org/10.1007/s10792-013-9835-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10792-013-9835-2

Keywords

Navigation