The efficiency of aranose combinations with gemcitabine and cisplatin was studied in experimental Lewis lung epidermoid carcinoma. Significant synergism of all the studied combinations and their satisfactory tolerance was demonstrated. The gemcitabine+cisplatin+aranose combination was significantly more effective than gemcitabine+cisplatin.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
L. V. Manzyuk, A. G. Borodkina, E. V. Artamonova, et al., Vestn. Rossiisk. Onkol. Nauch. Tsentra im. N. N. Blokhina, No. 2, 27-30 (2000).
N. M. Peretolchina, T. I. Klochkova, L. M. Mikhailova, et al., Aranose: A New Antitumor Drug [in Russian], Moscow (2000).
E. M. Treshalina, O. S. Zhukova, G. K. Gerasimova, et al., Manual of Experimental (Preclinical) Studies of New Drugs, Ed. R. U. Khabriev [in Russian], Moscow (2005), pp. 637-651.
B. A. Chabner and D. L. Longo, Cancer Chemotherapy and Biotherapy: Principles and Practice, Philadelphia (2001), pp. 678-699.
C. J. van Moorsel, H. M. Pinedo, K. Smid, et al., Eur. J. Cancer, 36, No. 18, 2420-2429 (2000).
C. J. van Moorsel, H. M. Pinedo, G. Veerman, et al., Br. J. Cancer, 80, No. 7, 981-990 (1999).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 12, pp. 674-677, December, 2009
Rights and permissions
About this article
Cite this article
Pokrovsky, V.S., Lesnaya, N.A., Romanenko, V.I. et al. Efficiency and Tolerance of Aranose Combinations with Cisplatin and Gemcitabine in Experimental Lung Cancer. Bull Exp Biol Med 148, 911–914 (2009). https://doi.org/10.1007/s10517-010-0850-2
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-010-0850-2