Summary
A case is reported of theophylline intoxication due to a dramatic decrease in theophylline clearance following concomitant administration of viloxazine.
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References
Hendeles L, Weinberger M (1983) Theophylline: A “state of the art” review. Pharmacotherapy 3: 2–44
Pinder RM, Brogden RN, Speight TM, Avery GS (1977) Viloxazine: A review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs 13: 401–421
Chiou WL, Gadalla MAF, Peng GW (1978) Method for the rapid estimation of the total body clearance and adjustment of dosage regimens in patients during a constant-rate intravenous infusion. J Pharmacokin Biopharm 6 [2]: 135–151
Gibaldi M, Perrier D (1975) Pharmacokinetics. Marcel Dekker, New York
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Laaban, J.P., Dupeyron, J.P., Lafay, M. et al. Theophylline intoxication following viloxazine induced decrease in clearance. Eur J Clin Pharmacol 30, 351–353 (1986). https://doi.org/10.1007/BF00541543
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DOI: https://doi.org/10.1007/BF00541543