Summary
The genetic study of two dwarf and spontaneous mutants of the diploid free-living nematode C. elegans, has been realised according to the particular methods imposed by the unbalanced self-fertilizing hermaphroditism usual to this animal and by the absence of fertility of the male mutants.
By combining crosses of hermaphrodite homozygous dwarfs with exceptional heterozygous males and the study of the progeny obtained by automixis of the hermaphrodite hybrids, it can be shown:
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1.
Dwarfness in each mutant strain is a recessive and single factor character.
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2.
Characteristics of the two types of mutants are controlled by two different genes which are independant (phenotype ratio of complementary hermaphrodites progeny: 9 N/7 n) and not sex-linked.
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3.
Expression of dwarfness requires that at least one gene should be double recessive.
The embryologic determination of dwarfness could correspond to a perturbation of the eutelie caracteristic of the nematodes.
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Communicated by C. Auerbach
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Dion, M., Brun, J.L. Cartographie génique du Nématode libre Caenorhabditis elegans, Maupas 1900, variété Bergerac. Molec. Gen. Genet. 112, 133–151 (1971). https://doi.org/10.1007/BF00267491
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DOI: https://doi.org/10.1007/BF00267491