Summary
Plastic microfluidic bioanalytical device arrays offer biochemical compatibility, low-cost mass production, and single-use disposability. We have designed, modeled, prototyped, and manufactured a range of plastic microfluidic devices for bioanalytical applications including DNA sequencing, nucleic acid fragment analysis, and high-throughput screening of pharmaceutical candidate compounds.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Harrison, D. J.; van den Berg, A., Micro Total Analysis Systems’ 98, Kluwer Academic Publishers, 1998.
Harrison, D. J.; Manz, A.; Fan, Z.; Lüdi, H.; Widmer, H.M. Anal Chem. 1992, 64, 1926–1932.
Jacobson, S. C; Hergenröder, R.; Moore, Jr., A. W.; Ramsey, J. M. Anal Chem. 1994, 66, 4127.
Woolley, A. T.; Mathies, R. A. Proc. Natl Acad. Sci. USA 1994, 97, 11348–11352.
Koutny, L.B.; Schmalzing, D.; Taylor, T. A.; Fuchs, M. Anal Chem. 1996, 68, 18–22.
Effenhauser, C. S.; Bruin, G. J. M.; Paulus, A.; Ehrat, M. Anal Chem. 1997, 69, 3451–3457.
McCormick, R.; Nelson, R.; Alonso, M. G.; Benvegnu, D.; Hooper, H. Anal. Chem. 1997, 69, 2626.
Sassi, A.; Cruzado, I.; Björnson, T.; Hooper, H.; Paulus, A. J. Chromatogr. A, 2000, 894, 203–217.
Soper, S.; Ford, S.; Xu, Y.; et al. J. Chromatogr A. 1999, 853, 107–120.
Backhouse, C.; Caamano, M.; Oaks, F.; Nordman, E.; Carrillo, A.; Johnson, B.; Bay, S. Electrophoresis 2000, 21, 150–156.
Liu, S.; Ren, H.; Gao, Q.; et al. Proc. Natl Acad. Sci. USA 2000, 97, 5369–5374.
Schmalzing, D.; Adourian, A.; Koutny, L.; et al. Anal Chem. 1998, 70, 2303–2310.
Burns, M.; Johnson, B.; Brahmasandra, S.; et al. Science 1998, 282, 484–487.
Guckel, H. Proc. IEEE 1998, 86, 1586–1593.
International Human Genome Sequencing Consortium, Nature 2001, 409, 860–921.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2001 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Boone, T.D. et al. (2001). Disposable Plastic Microfluidic Arrays for Applications in Biotechnology. In: Obermeier, E. (eds) Transducers ’01 Eurosensors XV. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59497-7_264
Download citation
DOI: https://doi.org/10.1007/978-3-642-59497-7_264
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-42150-4
Online ISBN: 978-3-642-59497-7
eBook Packages: Springer Book Archive