Abstract
In brain tissue there are two pathways by which choline and ethanolamine can be incorporated into a lipid-bound form. The first is the cytidine pathway originally described by Kennedy and Weiss (1956) for liver and the second, though it is probably a minor pathway, is a calciummediated exchange where the base is exchanged with that of an intact phospholipid (Ansell & Spanner, 1966; Porcellati, et al., 1971; Kanfer, 1972). In this account the first step of the cytidine pathway will be discussed in detail and in particular, this step in the nerve endings of brain.
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References
Abdel-Latif, A.A. & Smith, J.P. (1972) Biochem. Pharmacol. 21, 3005–3021.
Ansell, G.B. & Spanner, S. (1966) Biochem. J. 100, 50 P
Ansell, G.B. & Spanner, S. (1967) J. Neurochem. 14, 873–885.
Ansell, G.B. & Spanner, S. (1968) Biochem. J. 110, 201–206.
Ansell, G.B. & Spanner, S. (1974) J. Neurochem. 22, 1153–1155.
Ansell, G.B. & Spanner, S. (1975) Biochem. Pharmacol. 24, 1719–1723.
Ansell, G.B. & Spanner, S. (1976) Adv. Exp. Med. & Biol. 72, 161–168.
Arienti, G., Corrazi, L., Woelk, H. & Porcellati, G. (1976) J. Neurochem. 27, 203–210.
Cooper, P.H. & Hawthorne, J.N. (1975) Biochem. J. 150, 537–551.
De Pierre, J.W. & Karnovsky, M.L. (1973) J.Cell Biol. 56, 275–303.
Diamond, I. & Kennedy, E.P. (1969) J. Biol. Chem. 244, 3258–3263.
Dowdall, M.J., Barker, L.A. & Whittaker, V.P. (1972) Biochem. J. 130, 1081–1094.
Gardiner, J.E. (1961) Biochem. J. 81, 297–303
Gomez, M.V., Domino, E.F., Santiago, J.C. & Sellinger, O.Z. (1971). Neurobiology 1, 103–114.
Haubrich, D.R. (1973) J. Neurochem. 21, 315–328.
Kanfer, J.N. (1972) J. Lipid Res. 13, 468–476.
Kennedy, E.P. & Weiss, S. B. (1956) J. Biol. Chem. 222, 193–214.
Lunt, G.G. & Lapetina, E.G. (1970) Brain Res. 17, 164–167.
McCaman, R.E. (1962) J. Biol. Chem. 237, 672–676.
McCaman, R.E. & Cook, K. (1966) J. Biol. Chem. 241, 3390–3394.
Miller, E.K. & Dawson, R.M.C. (1972) Biochem. J. 126, 805–821.
Porcellati, G., Arienti, G., Pirotta, M. & Giorgini, D. (1971) J. Neurochem. 18, 1395–1417.
Schueler, F.W. (1960) Int. Rev. Neurobiol. 2, 77–97
Spanner, S. & Ansel, G.B. (1977) Biochem. Soc. Trans. 5, 164–165.
Strickland, K.P., Thompson, R.H.S. & Webster, G.R. (1956) J. Neurol. Neurosurg. Psychiat. 19, 12–16.
Sun, A.Y. & Sun, G.Y. (1976) Adv. Exp. Med. & Biol. 72, 169–197.
Weinhold, P.A. & Rethy, V.B. (1974) Biochemistry, 13, 5135–5141.
Yamamura, H.I. & Snyder, S.H. (1973) J. Neurochem. 21, 1355–1374.
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© 1978 Plenum Press, New York
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Spanner, S., Ansell, G.B. (1978). Choline and Ethanolamine Kinase Activity in the Cytoplasm of Nerve Endings from Rat Forebrain. In: Gatt, S., Freysz, L., Mandel, P. (eds) Enzymes of Lipid Metabolism. Advances in Experimental Medicine and Biology, vol 101. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9071-2_23
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DOI: https://doi.org/10.1007/978-1-4615-9071-2_23
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