Elsevier

Seminars in Immunology

Volume 12, Issue 6, December 2000, Pages 537-542
Seminars in Immunology

Regular Article
CD1d-restricted mouse Vα14 and human Vα24 T cells: lymphocytes of innate immunity

https://doi.org/10.1006/smim.2000.0276Get rights and content

Abstract

Mouse V α 14 T cells and their human homologs, V α 24 T cells, are prominent subsets of CD1d-restricted T cells. Here we discuss their striking similarities to B-1 B cells andγδ T cells and propose that these immune cells mediate various innate strategies in response to endogenous or exogenous danger signals.

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