Regular ArticleA New Locus for Hereditary Gingival Fibromatosis (GINGF2) Maps to 5q13–q22
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2014, Journal of Oral and Maxillofacial Surgery, Medicine, and PathologyCitation Excerpt :To date 4 loci for isolated HGF have been identified, on chromosomes 2p21 (GINGF1, MIM 135300), 5q13-q22 (GINGF2, MIM 605544), 2p23.3-p22.3 (GINGF3, MIM 609955) and 11p15 (GINGF4, MIM 611010). Sequencing of the 16 known genes, which mapped GINGF1, disclosed a heterozygous frameshift mutation in Son-of-Sevenless-1 (SOS-1) gene [9,10]. The most widely employed surgical approach is gingivectomy and gingivoplasty.
ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts
2024, Journal of Periodontal ResearchDouble heterozygous pathogenic mutations in KIF3C and ZNF513 cause hereditary gingival fibromatosis
2023, International Journal of Oral ScienceSurgical treatment of hereditary gingival fibromatosis by diode laser: Report of five rare cases in the same family
2023, Special Care in DentistryNew evidence of genetic heterogeneity causing hereditary gingival fibromatosis and ALK and CD36 as new candidate genes
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These authors contributed equally to this work.
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