Biochemical and Biophysical Research Communications
Regular ArticleGlucocorticoid Stimulates Primate but Inhibits Rodent α-Fetoprotein Gene Promoter☆
References (55)
- et al.
Stability of α-fetoprotein messenger RNA in mouse yolk sac
Dev. Biol.
(1982) - et al.
Albumin and α-fetoprotein gene expression in various nonhepatic rat tissues
J. Biol. Chem.
(1988) - et al.
Dexamethasone inhibits α-fetoprotein gene expression in developing mouse liver
Biochem. Biophys. Res. Commun.
(1979) - et al.
Tissue specific control of α-fetoprotein gene expression
Biochem. Biophys. Res. Commun.
(1984) - et al.
α-Fetoprotein biosynthesis and hepatocellular differentiation
Biochem. Biophys. Res. Commun.
(1982) - et al.
The expression of α-fetoprotein and albumin genes in rat liver during chemical carcinogenesis
Biochem. Biophys. Res. Commun.
(1982) - et al.
Analysis of the mechanism of glucocorticoid-mediated down regulation of the mouse α-fetoprotein gene
Biochim. Biophys. Acta
(1994) - et al.
Transcriptional regulation of α-fetoprotein expression by dexamethasone in human hepatoma cells
J. Biol. Chem.
(1989) - et al.
The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor
Biochimie
(1993) - et al.
Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
J. Lipid Res.
(1996)
Retinoic acid mediates down-regulation of the α-fetoprotein gene through decreased expression of hepatocyte nuclear factors
J. Biol. Chem.
A different combination of transcription factors modulates the expression of the human transferrin promoter in liver and Sertoli cells
J. Biol. Chem.
SV40-transformed simian cells support the replication of early SV40 mutants
Cell
Transcriptional regulation of human apolipoprotein genes ApoB, ApoCIII, and ApoAII by members of the steroid hormone receptor superfamily HNF-4, ARP 1, EAR-2, and EAR-3
J. Biol. Chem.
Suppression of glutathione transferase P expression by glucocorticoid
Biochem. Biophys. Res. Commun.
Regulation of α-fetoprotein gene expression by antagonism between AP-1 and the glucocorticoid receptor at their overlapping binding site
J. Biol. Chem.
Identification of a negative glucocorticoid response element in the rat type 1 vasoactive intestinal polypeptide receptor gene
J. Biol. Chem.
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
Cell
Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids
J. Biol. Chem.
Tissue specificity of α-fetoprotein messenger RNA expression during mouse embryogenesis
EMBO J.
Hormonal regulation of α1 foetoprotein
Nature
Hormonal modulation of α-fetoprotein gene expression in newborn rat livers
Nucleic Acids Res.
Glucocorticosteroid suppression of α1-fetoprotein synthesis in developing rat liver. Evidence for selective gene repression at the transcriptional level
Biochemistry
Hormonal control of the expression of α fetoprotein in newborn rats. Evidence for a selective action of glucocorticoids on gene transcription
Ann. Endocrinol. (Paris)
Enhancer and promoter elements directing activation and glucocorticoid repression of the α1-fetoprotein gene in hepatocytes
Mol. Cell. Biol.
Dexamethasone inhibition of rat hepatoma growth and α-fetoprotein synthesis
Cancer Res.
Regulation and activities of α-fetoprotein
Crit. Rev. Eukaryot. Gene Expression
Cited by (14)
Therapeutic efficacy of improved α-fetoprotein promoter-mediated tBid delivered by folate-PEI600-cyclodextrin nanopolymer vector in hepatocellular carcinoma
2014, Experimental Cell ResearchCitation Excerpt :It is not sure whether one bp difference (−119 vs −120) would generate such complete different results. However, the species difference between human and mouse is likely to have an impact on the generation of the contrary results, which may resemble the situation of the opposite effects of glucocorticoid on the AFP promoter activity from primate and rodent [11]. Regarding the non-significant difference between some AFP promoters that harbor SNPs identified in HCC samples and the wild-type AFP promoter, the negative result may be due to the fact that the SNPs identified in our samples are not located at the binding sites of the key cis-transcriptional elements.
Glucocorticoids regulate the human occludin gene through a single imperfect palindromic glucocorticoid response element
2008, Molecular and Cellular EndocrinologyGlucocorticoids and immunity: Mechanisms of regulation
2007, Psychoneuroimmunology, Two-Volume SetGlucocorticoids and Immunity: Mechanisms of Regulation
2006, PsychoneuroimmunologyMechanisms of glucocorticoid signalling
2004, Biochimica et Biophysica Acta - Gene Structure and ExpressionFunctional mapping of tissue-specific elements of the human α-fetoprotein gene enhancer
2004, Biochemical and Biophysical Research CommunicationsCitation Excerpt :Construction of plasmids with AFP enhancer elements. The plasmids, phAF[−4995/+45]-Luc, phAF[−3744/+45]-Luc, phAF[−2953/+45]-Luc, are constructed using PCR amplification and then inserted into the SpeI and KpnI sites of phAF[−178/+45]-Luc [16]. The deletion mutants, phAF[−4995/−2953]-[−178/+45]-Luc and phAF[−4995/−3744]-[−871/+45]-Luc, were constructed by using convenient restriction enzymes.
- ☆
Abbreviations used: AFP, α-fetoprotein; GRE, glucocorticoid responsive elements; DR-1, direct repeat-1; GR, glucocorticoid receptor; RXR, retinoid X receptor; PPAR, peroxisome proliferator-activated receptor; PBS, phosphate buffered saline; Dex, dexamethasone; PCR, polymerase chain reaction; HNF, hepatocyte nuclear factor; Luc, luciferase; GSTP, glutathione S transferase P; and MMTV, mouse mammary tumor virus.
- 1
To whom correspondence should be addressed at Department of Biochemistry, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo 060-8638, Japan. Fax: +81-11-706-7865. E-mail: [email protected].