Biochemical and Biophysical Research Communications
Volume 255, Issue 3, 24 February 1999, Pages 580-586
Regular ArticleReduction of Caveolin 1 Gene Expression in Lung Carcinoma Cell Lines
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Fatty acylated caveolin-2 is a substrate of insulin receptor tyrosine kinase for insulin receptor substrate-1-directed signaling activation
2015, Biochimica et Biophysica Acta - Molecular Cell ResearchCitation Excerpt :Further studies are needed to identify the enzymes responsible for and address the regulatory mechanisms controlling palmitoylation and depalmitoylation of cav-2 by specific DHHC and APT, respectively, which localize in a particular intracellular compartment. Cav-2 is widely present and its expression is up-regulated in various tumor cells [46–49]. Micro-ribonucleic acid 199a-3p-targeted cav-2 regulates proliferation and survival of tumor cells [50].
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