Biochemical and Biophysical Research Communications
Volume 226, Issue 3, 24 September 1996, Pages 791-795
Regular ArticleActivation but Not Inactivation of theMTS1Gene Is Associated with Primary Colorectal Carcinomas☆
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Cited by (18)
Human colorectal cancers with an intact p16/cyclin D1/pRb pathway have up-regulated p16 expression and decreased proliferation in small invasive tumor clusters
2000, American Journal of PathologyCitation Excerpt :When tumor cells invade, they will confront a new microenvironment; for melanoma cells growing in vitro, the type of collagen affected the proliferation and growth arrest was observed in the presence of fibrillar type I collagen.22 Our results, as well as others, indicate that the expression of p16 is low in normal colonic mucosa in contrast to high p16 levels in a majority of CRCs.14,23 Nevertheless, loss of p16 has been described in many types of cancer and has also been observed in CRC.15,16
The p16(INK4a)/CDKN2A tumor suppressor and its relatives
1998, Biochimica et Biophysica Acta - Reviews on CancerActivation of a prometastatic gene expression program in hypoxic neuroblastoma cells
2009, Endocrine-Related Cancer
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Abbreviations:MTS1,multiple tumor suppressor 1; DMSO, dimethyl sulfoxide;G3PDH,glyceraldehyde 3-phosphate dehydrogenase; RT-PCR, reverse transcription-polymerase chain reaction.
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