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Adjustable versus non‐adjustable sutures for strabismus

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Abstract

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Background

Strabismus, or squint, can be defined as a deviation from perfect ocular alignment and can be classified in many ways according to its aetiology and presentation. Treatment can be broadly divided into medical and surgical options, with a variety of surgical techniques being available, including the use of adjustable or non‐adjustable sutures for the extraocular muscles. There exists an uncertainty as to which of these techniques produces a better surgical outcome, and also an opinion that the adjustable suture technique may be of greater benefit in certain situations.

Objectives

To examine whether adjustable or non‐adjustable sutures are associated with a more accurate long‐term ocular alignment following strabismus surgery and to identify any specific situations in which it would be of benefit to use a particular method.

Search methods

We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2010, Issue 3), MEDLINE (January 1950 to September 2010), EMBASE (January 1980 to September 2010), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to September 2010), the metaRegister of Controlled Trials (mRCT) (www.controlled‐trials.com) and ClinicalTrials.gov (www.clinicaltrials.gov). There were no date or language restrictions in the electronic searches for trials. The electronic databases were last searched on 27 September 2010. We also contacted experts in the field for further information.

Selection criteria

We planned to include only randomised controlled trials (RCTs) comparing adjustable to non‐adjustable sutures for strabismus surgery.

Data collection and analysis

We did not find any studies that met the inclusion criteria for this review.

Main results

We did not find any studies that met the inclusion criteria for this review, therefore none were included for analysis. Results of non‐randomised studies that compared these techniques are reported.

Authors' conclusions

No reliable conclusions could be reached regarding which technique (adjustable or non‐adjustable sutures) produces a more accurate long‐term ocular alignment following strabismus surgery or in which specific situations one technique is of greater benefit than the other. High quality RCTs are needed to obtain clinically valid results and to clarify these issues. Such trials should ideally a) recruit participants with any type of strabismus or specify the subgroup of participants to be studied, for example, thyroid, paralytic, non‐paralytic, paediatric; b) randomise all consenting participants to have either adjustable or non‐adjustable surgery prospectively; c) have at least six months of follow‐up data; and d) include re‐operation rates as a primary outcome measure.

PICOs

Population
Intervention
Comparison
Outcome

The PICO model is widely used and taught in evidence-based health care as a strategy for formulating questions and search strategies and for characterizing clinical studies or meta-analyses. PICO stands for four different potential components of a clinical question: Patient, Population or Problem; Intervention; Comparison; Outcome.

See more on using PICO in the Cochrane Handbook.

Plain language summary

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Adjustable versus non‐adjustable sutures for the eye muscles in strabismus surgery

Strabismus occurs when the eye deviates from its normally perfect alignment, and can be corrected with surgery. A variety of surgical techniques are available, including the use of adjustable or non‐adjustable sutures for the muscles surrounding the eye. There is uncertainty as to which of these suture techniques results in a more accurate alignment of the eye, and whether there are specific situations in which it is of benefit to use a particular technique. This review could not find enough evidence to answer these questions and suggests that more research is needed. The review authors used existing evidence to propose that future randomised controlled trials should directly compare the adjustable to the non‐adjustable suture technique, in co‐operative patients with any type of strabismus. Trials should have a minimum of six months follow‐up and should include important outcome measures such as re‐operation rates, accuracy of ocular alignment, complications, economics and patient satisfaction. The information generated from well‐designed studies could support a change in the conventional surgical management of strabismus and help to direct planning of surgical training.